The Effect of Virtual Reality on Pain and Memory.

NCT06871423 | Completed

• 1 other identifier: VRAnalgesia2022
• Study Type: interventional
• Target: 16
• Locations: 1 country
• Sites: 1

Brief Summary

The effect of Virtual Reality on pain and memory.

Conditions

Healthy Adult

Keywords

virtual reality; pain; distraction

Outcome Measures

Primary Outcomes (2)

• Pain Memory Recall Test

  After each brief thermal stimulus set, participants were asked to recall the exact pattern of the most recent sequence of 5 brief thermal stimuli, recalled in exact order, via our five question "pain memory recall test" (min = 0%, max -= 100% correct). Lower % correct scores mean less accurate memory (poorer outcome).

  After each brief pain stimulus set, participants performed a brief distractor task before completing the Pain Memory Recall Test. The Pain Memory Recall Test was completed within 5 minutes after each brief thermal stimulus set.

• Participants subjective rating of the accuracy of their memory for painful stimuli

  Using a graphic rating scale, on a scale from zero (min) to 10 (max), participants rated how accurately they could remember their pain during No Virtual Reality vs during Virtual Reality. Higher scores indicated higher accuracy and more positive outcome.

  measured within 10 minutes after each pain stimulus set

Secondary Outcomes (1)

• Presence ratings using Graphic Rating Scales

  measured within 10 minutes after participant was in virtual reality

Study Arms (2)

No Virtual Reality

NO INTERVENTION

No Virtual Reality during painful stimuli

Immersive VR

EXPERIMENTAL

immersive virtual reality during painful stimuli

Behavioral: distraction

Interventions

distraction BEHAVIORAL

distraction via virtual reality game named "Waltz of the Wizards" aka magic bowl.

Immersive VR

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• must be English speaking (but English does not necessarily need to be native/first language).
• must be willing to follow our UW approved instructions,

You may not qualify if:

• Not capable of indicating pain intensity
• Not capable of filling out study measures
• Non-English-speaking
• Extreme susceptibility to motion sickness
• Seizure history
• Unusual sensitivity or lack of sensitivity to pain
• Sensitive skin
• sensitive feet
• migraines
• cold symptoms
• Diabetes
• Or if you are under 18 years old

Sponsors & Collaborators

• University of Washington: lead

Study Sites (1)

University of Washington

Seattle, Washington, 98195, United States

Location

MeSH Terms

Conditions

Pain

Interventions

Osteogenesis, Distraction

Condition Hierarchy (Ancestors)

Neurologic Manifestations; Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

Bone Lengthening; Orthopedic Procedures; Surgical Procedures, Operative

Study Officials

• Hunter G Hoffman, Ph.D.

  University of Washington

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: PARTICIPANT
• Purpose: BASIC SCIENCE
• Intervention Model: CROSSOVER
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Director, Virtual Reality Research Center at the Human Photonics Lab; Research Scientist:Dept of Mechanical Engineering

Model Details: Using a repeated measures within-subject crossover design with treatment order randomized, with healthy volunteers,

Study Record Dates

• First Submitted: March 1, 2025
• First Posted: March 12, 2025
• Study Start: January 3, 2025
• Primary Completion: March 1, 2025
• Study Completion: March 1, 2025
• Last Updated: March 13, 2025

Record last verified: 2025-03

Data Sharing

• IPD Sharing: Will share
• Time Frame: Beginning 3 months after the publication of the results, and ending 3 years after the publication of results
• Access Criteria: All data is already de-identified. Only de-identified data will be shared. The datasets used and/or analyzed during the current study will be made available from the corresponding author on reasonable request. All de-identified IPD that underlie our results in a publication will be shared.

Locations

US (1)