NCT06869720

Brief Summary

This study aims to investigate the effects of elliptical exercise on the six-minute walk test and quality of life in patients with chronic obstructive pulmonary disease (COPD) to identify the most efficient exercise training method.

Trial Health

30
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Timeline
Completed

Started Mar 2025

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
withdrawn

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

March 6, 2025

Completed
5 days until next milestone

First Posted

Study publicly available on registry

March 11, 2025

Completed
Same day until next milestone

Study Start

First participant enrolled

March 11, 2025

Completed
5 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 31, 2025

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

July 31, 2025

Completed
Last Updated

February 4, 2026

Status Verified

March 1, 2025

Enrollment Period

5 months

First QC Date

March 6, 2025

Last Update Submit

February 2, 2026

Conditions

COPD (Chronic Obstructive Pulmonary Disease)

Keywords

Pulmonary rehabilitationEccentric exerciseChronic obstructive pulmonary diseaseCardiopulmonary fitnessFunctional fitness

Outcome Measures

Primary Outcomes (3)

  • six minute walk test

    functional performance

    12 weeks

  • time up and go

    functional performance

    12 weeks

  • stairs ascending and descending walking time

    functional performance

    12 weeks

Study Arms (2)

Intervention Group: eccentric cycling exercise

EXPERIMENTAL

Received eccentric cycling exercise

Device: Eccentric bike

Control group

ACTIVE COMPARATOR

Undergoing conventional treatment

Other: conventional group

Interventions

Eccentric bikeDEVICE

Received eccentric cycling exercise

Intervention Group: eccentric cycling exercise
conventional groupOTHER

Received conventional treatment

Control group

Eligibility Criteria

Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

  • Having undergone pulmonary rehabilitation for more than 3 months
  • Sign the written informed consent form
  • FEV1/FVC \< 0.70
  • Approval for exercise training granted by a specialist physician's assessment
  • Specialist physician's approval for exercise training

You may not qualify if:

  • Existing of tracheostomy
  • Those who use oxygen therapy or ventilator at home
  • Severe heart failure (NYHA III-IV)
  • Neuromuscular disease
  • Acute exacerbation within the past three months
  • Those who are unable to cooperate with the cardiopulmonary exercise test

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Fu Jen Catholic University Hospital, Fu Jen Catholic University

New Taipei City, 24352, Taiwan

Location

MeSH Terms

Conditions

Pulmonary Disease, Chronic Obstructive

Condition Hierarchy (Ancestors)

Lung Diseases, ObstructiveLung DiseasesRespiratory Tract DiseasesChronic DiseaseDisease AttributesPathologic ProcessesPathological Conditions, Signs and Symptoms

Study Officials

  • Ke-Yun Chao, PhD

    Fu Jen Catholic University

    PRINCIPAL INVESTIGATOR
0

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
OTHER
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Assistant Professor

Study Record Dates

First Submitted

March 6, 2025

First Posted

March 11, 2025

Study Start

March 11, 2025

Primary Completion

July 31, 2025

Study Completion

July 31, 2025

Last Updated

February 4, 2026

Record last verified: 2025-03

Data Sharing

IPD Sharing
Will not share

Locations

TW(1)