Erector Spinae Plane Block Versus Serratus Anterior Plane Block

NCT06862752 | Completed

• 1 other identifier: leyla-25
• Study Type: interventional
• Target: 80
• Locations: 1 country
• Sites: 1

Brief Summary

the aim of the study compare the analgesic effect of erector spinae block and serratus anterior block in breast surgery

Conditions

Post Operative Pain; Opioid-Related Disorders

Keywords

post operative pain; opioid consumption; erector spinae block; serratus anterior plane block

Outcome Measures

Primary Outcomes (1)

• Opioid consumption

  Tramadol consumption in Patient Controlled Analgesia device postoperative 24 hours.

  24 hour

Secondary Outcomes (5)

• Pain assessed by NRS

  24 hour

• Rate of opioid related side effects

  24 hour

• Blooad loss

  during surgery

• Remifentanil consumption

  during surgery

• Length of stay in hospital

  30 days

Study Arms (2)

ESP block group

ACTIVE COMPARATOR

Bilateral ultrasound guided erector spine plane (ESP) block will be performe preoperatively at T5 level. 20 mL local anesthetics (10 mL 0.5% bupivacaine + 10 mL serum physiologic % l) will be injected deep to the erector spinae muscle

Procedure: erector spine plane (ESP) block

SAP Block grup

OTHER

Bilateral ultrasound guided serratus plane block with 20 ml %0,25 bupivacaine at the midaxillary 5. Rib

Procedure: Serratus Anterior Plane Block

Interventions

erector spine plane (ESP) block PROCEDURE

Bilateral ultrasound guided erector spine plane (ESP) block will be performe preoperatively at T5 level. 20 mL local anesthetics (10 mL 0.5% bupivacaine + 10 mL serum physiologic % l) will be injected deep to the erector spinae muscle.

ESP block group

Serratus Anterior Plane Block PROCEDURE

Bilateral ultrasound guided serratus plane block with 20 ml %0,25 bupivacaine at the midaxillary 5. Rib

SAP Block grup

Eligibility Criteria

• Age: 18 Years - 65 Years
• Sex: female
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• American Society of Anesthesiologists (ASA) I-II,
• years of age, adult,
• female patients
• undergoing elective breast reduction surgery

You may not qualify if:

• Allergy to amide-type local anesthetics
• Infection at the block injection site
• Severe obesity (BMI \> 35 kg/m2)
• Liver or renal deficiency
• Patients with anatomical deformities
• Recent use of analgesic drugs
• Patient refusal or inability to consent

Sponsors & Collaborators

• Sisli Hamidiye Etfal Training and Research Hospital: lead

Study Sites (1)

Sisli etfal research and training hospital

Istanbul, 34371, Turkey (Türkiye)

Location

MeSH Terms

Conditions

Pain, Postoperative; Opioid-Related Disorders

Interventions

Parapsychology; Dental Occlusion

Condition Hierarchy (Ancestors)

Postoperative Complications; Pathologic Processes; Pathological Conditions, Signs and Symptoms; Pain; Neurologic Manifestations; Signs and Symptoms; Narcotic-Related Disorders; Substance-Related Disorders; Chemically-Induced Disorders; Mental Disorders

Intervention Hierarchy (Ancestors)

Behavioral Sciences; Behavioral Disciplines and Activities; Dentistry; Dental Physiological Phenomena; Digestive System and Oral Physiological Phenomena

Study Officials

• AYSE SURHAN CINAR

  SISLI HAMIDIYE ETFAL RESEARCH AND TRAINING

  STUDY CHAIR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: TRIPLE
• Who Masked: PARTICIPANT, INVESTIGATOR, OUTCOMES ASSESSOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: associate professor

Study Record Dates

• First Submitted: March 1, 2025
• First Posted: March 6, 2025
• Study Start: April 1, 2025
• Primary Completion: January 1, 2026
• Study Completion: January 15, 2026
• Last Updated: February 18, 2026

Record last verified: 2026-02

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)