Upper Extremity Exercise Capacity Of Breast Cancer

NCT06859593 | Completed

• 1 other identifier: FTREK 25/01
• Study Type: observational
• Target: 48
• Locations: 1 country
• Sites: 1

Brief Summary

Breast cancer is one of the most common cancers among women worldwide, with an incidence rate of up to 16%. Although survival can be improved with early diagnosis and more effective therapies, physical complications such as lymphedema, upper extremity dysfunction and chronic pain are common during and/or after breast cancer treatments. In addition, lymphedema can cause symptoms such as decreased muscle strength and range of motion of the upper extremity, pain and fatigue, resulting in activity limitations and decreased functional level of the upper extremity.

Conditions

Breast Cancer Survivor; Healty Controls

Keywords

breast cancer; upper extremity; 6-minute pegboard and ring test; exercise capacity

Outcome Measures

Primary Outcomes (1)

• Upper Extremity Exercise Capacity

  6-Minute Pegboard and Ring Test

  One Year

Secondary Outcomes (3)

• Evaluation of Upper Extremity Functionality

  One Year

• Lymphedema Evaluation

  One Year

• Measurement of arm length, arm and forearm circumference

  One Year

Study Arms (2)

Breast Cancer Group

Inclusion criteria were to be between 18-65 years of age, to volunteer to participate in the study, to have Stage I-III breast cancer, to have at least 15 months after breast cancer surgery, to have six months after active breast cancer treatment (i.e. surgery/chemotherapy), to have no problems in reading and/or understanding the scales and to be able to cooperate with the tests. Exclusion criteria were the presence of active infection, musculoskeletal and neurologic disease that may affect exercise performance, symptomatic heart disease, neurologic disease or other clinical diagnosis that may affect cognitive status.

Diagnostic Test: Upper Extremity Exercise Capacity, 6-Minute Pegboard And Ring Test

Control Group

The inclusion criteria were to be between 18-65 years of age, to be willing to participate in the study, to have no problems in reading and/or understanding the scales and to be able to cooperate with the tests. Exclusion criteria were having any orthopedic or neuromuscular condition that would interfere with walking or exercise performance, having any chronic disease, or having psychiatric disorders or mental disorders that might interfere with cooperation or compliance with exercise tests.

Diagnostic Test: Upper Extremity Exercise Capacity, 6-Minute Pegboard And Ring Test

Interventions

Upper Extremity Exercise Capacity, 6-Minute Pegboard And Ring Test DIAGNOSTIC_TEST

Upper Extremity Exercise Capacity

Breast Cancer Group; Control Group

Eligibility Criteria

• Age: 18 Years - 65 Years
• Sex: female
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

Patients between the ages of 18-65 years who are diagnosed with breast cancer at Hacettepe University Hospital, Department of Internal Medicine, Division of Medical Oncology, and who volunteer to participate in the study will be included in the study. For healthy groups, age and gender appropriate volunteers will be recruited for the study

You may qualify if:

• Breast Cancer Group:
• Being between 18-65 years of age,
• Volunteering to participate in the research,
• Stage I-III breast cancer,
• At least 15 months after breast cancer surgery,
• Six months after active breast cancer treatment (i.e. surgery/chemotherapy),
• No problems in reading and/or understanding the scales and being able to cooperate with the tests,
• Healthy group:
• Age between 18-65 years,
• Volunteering to participate in the research,
• No problems in reading and/or understanding the scales and being able to cooperate with the tests.

You may not qualify if:

• Breast Cancer Group:
• Presence of active infection,
• Musculoskeletal and neurological diseases that may affect exercise performance, symptomatic heart disease,
• Having a neurological disease or other clinical diagnosis that may affect cognitive status.
• Healthy group:
• Having any orthopedic or neuromuscular condition that would interfere with walking or exercise performance,
• Having any chronic disease or psychiatric disorders or mental impairments that may interfere with cooperation or compliance with exercise tests

Sponsors & Collaborators

• Hacettepe University: lead

Study Sites (1)

Hcettepe University, Ankara, State 06100

Ankara, State, 06100, Turkey (Türkiye)

Location

MeSH Terms

Conditions

Breast Neoplasms

Condition Hierarchy (Ancestors)

Neoplasms by Site; Neoplasms; Breast Diseases; Skin Diseases; Skin and Connective Tissue Diseases

Study Officials

• Melda Saglam, PhD

  Hacettepe University

  STUDY CHAIR

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Professor

Study Record Dates

• First Submitted: February 28, 2025
• First Posted: March 5, 2025
• Study Start: March 1, 2025
• Primary Completion: May 1, 2025
• Study Completion: June 1, 2025
• Last Updated: July 9, 2025

Record last verified: 2025-07

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)