NCT06847659

Brief Summary

This study aims to evaluate the effectiveness of prewarming methods in preventing intraoperative hypothermia in patients undergoing HoLEP surgery. Designed as a randomized controlled study, patients who receive prewarming will be compared with those in the control group.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
106

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Mar 2025

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
not yet recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

February 18, 2025

Completed
8 days until next milestone

First Posted

Study publicly available on registry

February 26, 2025

Completed
3 days until next milestone

Study Start

First participant enrolled

March 1, 2025

Completed
4 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 30, 2025

Completed
2 months until next milestone

Study Completion

Last participant's last visit for all outcomes

August 31, 2025

Completed
Last Updated

February 26, 2025

Status Verified

February 1, 2025

Enrollment Period

4 months

First QC Date

February 18, 2025

Last Update Submit

February 21, 2025

Conditions

Outcome Measures

Primary Outcomes (1)

  • Time to onset of intraoperative hypothermia.

    Time to develop intraoperative hypothermia (when body temperature drops below 36°C)

    intraoperatively

Secondary Outcomes (5)

  • Hemodynamic parameters

    intraoperatively

  • Volume of irrigation fluid used

    intraoperatively

  • Changes in body temperature

    intraoperatively

  • Hemodynamic parameters

    intraoperatively

  • respiratory parameter

    intraoperatively

Study Arms (2)

Prewarming Group

EXPERIMENTAL

Patients will receive 10 minutes of 43°C forced-air warming and 41°C prewarmed intravenous fluid before surgery. Surgery will begin following the standard induction of general anesthesia once patients are in the operating room. An air blower set to 43°C will maintain patient warmth throughout the procedure.

Diagnostic Test: intraoperative body temperature

Control Group

OTHER

No prewarming will be applied. Surgery will begin following the standard induction of general anesthesia once patients are in the operating room. An air blower set to 43°C will maintain patient warmth throughout the procedure.

Diagnostic Test: intraoperative body temperature

Interventions

Body temperature measurement with esophageal probe

Control GroupPrewarming Group

Eligibility Criteria

Age18 Years+
Sexmale
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Male patients aged 18 years and older
  • Patients undergoing HoLEP surgery under general anesthesia
  • Patients who consent to participate in the study

You may not qualify if:

  • Patients who refuse to participate in the study.
  • Patients unable to read, understand, or sign the informed consent form.
  • Hemodynamically unstable patients.
  • Patients with a preoperative or intraoperative body temperature \>37°C.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Ankara City Hospital Bilkent

Ankara, Turkey (Türkiye)

Location

Central Study Contacts

Betül Güven Aytaç, Assoc.prof.

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
DIAGNOSTIC
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Ankara City Hospital Bilkent

Study Record Dates

First Submitted

February 18, 2025

First Posted

February 26, 2025

Study Start

March 1, 2025

Primary Completion

June 30, 2025

Study Completion

August 31, 2025

Last Updated

February 26, 2025

Record last verified: 2025-02

Locations