Combining Motor Imagery and Tendon Vibration on the Effectiveness of Motor Imagery
IMVT
Comparison of Three Modalities of Combining Motor Imagery and Tendon Vibration on the Effectiveness of Motor Imagery
2 other identifiers
interventional
33
1 country
1
Brief Summary
Kinesthetic motor imagery (kMI) involves imagining the sensations of movement, activating brain regions similar to actual movement execution. It is widely used to maintain or restore motor functions, particularly in rehabilitation. Tendon vibration (TV), which stimulates proprioceptive receptors can also enhance corticospinal excitability and promote neuroplasticity. This project investigates the coupling of kMI and TV through three modalities: simultaneous application, TV application between kMI trials, or pre-application of TV to precondition the nervous system before kMI trials. The effectiveness and quality of kMI will be assessed by corticospinal excitability measurements using transcranial magnetic stimulation and EEG measures. Conducting this study in healthy participants will inform the development of optimized clinical interventions for immobilized or mobility-reduced patients.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P25-P50 for not_applicable
Started Mar 2025
Typical duration for not_applicable
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
February 20, 2025
CompletedFirst Posted
Study publicly available on registry
February 25, 2025
CompletedStudy Start
First participant enrolled
March 11, 2025
CompletedPrimary Completion
Last participant's last visit for primary outcome
March 1, 2027
ExpectedStudy Completion
Last participant's last visit for all outcomes
March 1, 2027
February 25, 2025
February 1, 2025
2 years
February 20, 2025
February 20, 2025
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Optimization of kMI
We will measure corticospinal excitability. This will be assessed by the area (in mV.%) under the curve representing the amplitude of motor-evoked potentials (MEPs, in mV) recorded via electromyography, as a function of transcranial magnetic stimulation intensity (in % of the stimulator's maximal output) required to evoke these potentials.
30 minutes
Study Arms (3)
Simultaneous application of TV and kMI
EXPERIMENTALSimultaneous application of Tendon Vibration and Kinesthesic Motor Imagery
TV application between kMI trials
EXPERIMENTALTendon Vibration application between Kinesthesic Motor Imagery
TV as a pre-conditionning for kMI
EXPERIMENTALTendon Vibration application as a pre-conditionning for Kinesthesic Motor Imagery
Interventions
We use the VIBRAMOOV PHYSIO device which delivers local muscle vibrations at frequencies of 80 Hz and an amplitude of 1 mm.
kMI is a mental technique in which an individual visualizes performing a movement without physically executing it. This process involves the internal representation of the sensations associated with the movement, engaging neural pathways similar to those activated during actual physical movement. kMI stimulates key motor and sensory areas in the brain, promoting neuroplasticity and enhancing motor performance.
Eligibility Criteria
You may qualify if:
- Men or women aged 18 to 50 years.
- Affiliated with or beneficiaries of a social security system.
- Provided written informed consent freely after being informed of the study's purpose, procedures, and potential risks.
You may not qualify if:
- History of pathology or surgery affecting upper limb motor function within 6 months prior to the study.
- Chronic neurological, motor, or psychiatric disorders.
- Use of neuroactive substances likely to alter corticospinal excitability (e.g., hypnotics, antiepileptics, psychotropics, muscle relaxants) during the study period.
- Contraindications to transcranial magnetic stimulation
- Simultaneous participation in another interventional study or participation in such a study within 30 days prior to this study.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
IRMIS-Hôpital Nord
Saint-Etienne, France, 42055, France
Study Officials
- PRINCIPAL INVESTIGATOR
Léonard FEASSON, PhD
Centre Hospitalier Universiatire de SAINT-ETIENNE
Central Study Contacts
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- NONE
- Purpose
- BASIC SCIENCE
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
February 20, 2025
First Posted
February 25, 2025
Study Start
March 11, 2025
Primary Completion (Estimated)
March 1, 2027
Study Completion (Estimated)
March 1, 2027
Last Updated
February 25, 2025
Record last verified: 2025-02
Data Sharing
- IPD Sharing
- Will not share
This study is being conducted in a single department of the ST-ETIENNE University Hospital.