NCT06844968

Brief Summary

Intense physical exercise can lead to micro-damage to tissues and activation of inflammatory processes, the body's natural response to exercise-related metabolic stress. Monitoring inflammation and fatigue will enable the observation of athletes in terms of post-exercise regeneration and muscle adaptation to physical effort. The obtained results will allow for estimating the level of fatigue, minimizing the risk of injury, and will show the rate of post-exercise regeneration or its absence.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
40

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Mar 2024

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

March 1, 2024

Completed
9 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

November 30, 2024

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

November 30, 2024

Completed
1 month until next milestone

First Submitted

Initial submission to the registry

January 9, 2025

Completed
2 months until next milestone

First Posted

Study publicly available on registry

February 25, 2025

Completed
Last Updated

February 25, 2025

Status Verified

January 1, 2025

Enrollment Period

9 months

First QC Date

January 9, 2025

Last Update Submit

February 21, 2025

Conditions

Keywords

rowersEPOVEGFhypoxanthineglycogenathletes

Outcome Measures

Primary Outcomes (5)

  • EPO (erythropoietin) level

    Immunoenzymatic assay method using a diagnostic ELISA Kit

    Immediately before the ergometer test, immediately after and 3 hours after the test

  • VEGF (vascular endothelial growth factor) level

    Immunoenzymatic assay method using a diagnostic ELISA Kit

    Immediately before the ergometer test, immediately after and 3 hours after the test

  • Hypoxanthine (Hx) level

    Immunoenzymatic assay method using a diagnostic ELISA Kit

    Immediately before the ergometer test, immediately after and 3 hours after the test

  • Glycogen level

    Immunoenzymatic assay method using a diagnostic ELISA Kit

    Immediately before the ergometer test, immediately after and 3 hours after the test

  • Glucose level

    Using an Accu-Chek Active glucometer (Roche, Germany)

    Immediately before the ergometer test, immediately after and 3 hours after the test

Study Arms (1)

Physical effort

OTHER

The effort on the rowing ergometer, based on swimming a specified distance in the shortest possible time.

Other: Physical effort

Interventions

The examined rowers will be subjected to an effort on a rowing ergometer, consisting of covering a designated distance in the shortest possible time.

Also known as: Rowing ergometer test
Physical effort

Eligibility Criteria

Age19 Years - 23 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • members of the Polish Youth Rowing Team - competitors officially called up to the Polish national rowing team,
  • no musculoskeletal injuries that would prevent them from performing the exercise test,
  • written consent of the competitor to participate in the study.

You may not qualify if:

  • anti-inflammatory drugs, other supplements in the last 3 months before starting the study,
  • failure to complete the test,
  • current injury, post-traumatic condition, illness,
  • lack of informed consent of the athlete.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Poznań University of Physical Education, Faculty of Physical Culture in Gorzów Wielkopolski

Gorzów Wielkopolski, Polska, 66-400, Poland

Location

MeSH Terms

Interventions

Physical Exertion

Intervention Hierarchy (Ancestors)

Musculoskeletal Physiological PhenomenaMusculoskeletal and Neural Physiological Phenomena

Study Officials

  • Anna Kasperska, PhD

    Poznań University of Physical Education, Faculty of Sport Sciences in Gorzów Wielkopolski, Poland;

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
OTHER
Intervention Model
SINGLE GROUP
Model Details: A group of rowers subjected to an efford on a rowing ergometer. The examined rowers group will be subjected to an effort on a rowing ergometer, consisting of covering a designated distance in the shortest possible time.
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

January 9, 2025

First Posted

February 25, 2025

Study Start

March 1, 2024

Primary Completion

November 30, 2024

Study Completion

November 30, 2024

Last Updated

February 25, 2025

Record last verified: 2025-01

Data Sharing

IPD Sharing
Will not share

Locations