Physiologic Adaptations to Interval and Continuous Running at Low Volume and Vigorous Intensity Over 14-Weeks.

NCT01816451 | Completed Results DMC

• 1 other identifier: UFRJ-2010
• Study Type: interventional
• Target: 35
• Locations: 1 country
• Sites: 1

Brief Summary

The purpose of this study was to verify physiological responses to constant-load (continuous) vs. variable-intensity (interval) during 14 weeks of aerobic exercise on active men. The hypothesis was that would be differences in physiological variables on distinct modes of execution performed on the treadmill over a period of 14 weeks of training.

Conditions

Exhaustion - Physiological

Keywords

aerobic capacity; cardiorespiratory training; blood lactate concentration; heart rate

Outcome Measures

Primary Outcomes (8)

• Relative Maximal Oxygen Uptake

  The relative maximal oxygen uptake was taken by individual connected to a metabolic gas analyzer (VO-2000, Aerosport, Medgraphics, St. Paul, Minnesota) through which the gas samples were collected and measured each 10 seconds during the test. The participants were submitted to a ramp protocol with an initial velocity of 8.0 km/h (0% of inclination), progressive increments, a final velocity of 18 km/h (2% de inclination). The duration was equal to 10 minutes or until voluntary exhaustion.

  Pre and post 14 weeks

• Absolute Maximal Oxygen Uptake

  The absolute maximal oxygen uptake was taken by individual connected to a metabolic gas analyzer (VO-2000, Aerosport, Medgraphics, St. Paul, Minnesota) through which the gas samples were collected and measured each 10 seconds during the test. The participants were submitted to a ramp protocol with an initial velocity of 8.0 km/h (0% of inclination), progressive increments, a final velocity of 18 km/h (2% de inclination). The duration was equal to 10 minutes or until voluntary exhaustion.

  Pre and post 14 weeks

• Total Time Reaching on Maximal Test (tVO2max)

  The criterion for determining the total time reaching in maximal VO2 test was associated with the time immediately preceding heart rate shown a reduction of five or more beats.

  Pre and post 14 weeks/46 sessions of training

• Heart Rate on Maximal Test

  The HR was collected pre and post training on maximal VO2 test. Initially, with the individual on the treadmill (Inbrasport Master Super, Porto Alegre, Brazil), electrodes (Micromed) were placed at the manubrium, right and left iliac crest for measured heart rate (HR) (derivation CM5) and were connected to an electromyography equipment (Micromed®). HR values were visualized through Elite software (Micromed Biotechnology, Brasilia, Brazil).

  Pre and post 14 weeks at rest (5 min sitting; before start the test), during the test (to determine max), and 60s and 120s immediately after the end of the test (on sitting position)

• Blood Lactate Concentrations on Maximal Test

  Capillary blood samples (25 µl) were obtained from the finger of each subject during all tests and the \[La\] were measured using an (Accutrend®Plus Roche Diagnostics Gesellschaft mit beschränkter Haftung , Mannheim, Germany). The measuring range was 0.8-22 millimole (mM). The sample is collecting (Accu-Chek® Softclix) and first applied to a coded yellow test strip (Accutrend Blood measure-Roche) with a reagent chemical substance. Blood was added to the strip by letting it drip from a finger; in accordance with the instrument's instructions. The finger never touched the strip's pad in order to exclude any possible interference due to the sweat. All \[La\] were collected by a single, experienced investigator.

  Pre and post 14 weeks/46sessions on rest (5 min sitting position; before start the test); 1-3-5 min immediately after the end of the test (on sitting position).

• Body Mass (BM)

  To measure body mass Filizola scales with a stadiometer was used.

  Body Mass was collected pre and post training

• Rate of Perceived Exertion (RPE) on Maximal Test

  The RPE was collected at maximal test (see description of test on outcome measure "Maximal Oxygen Uptake"). Relative to overall feelings were collected by Category Ratio Scale (CR10) during the last 15 s of each stage using the Borg category (0 - 10) scale. Instructions for RPE were that "0" corresponds to rest, and "9 - 10" corresponds to maximal exertion. This verbal procedure was explained before initiating exercise.

  Pre and post 14 weeks/46 sessions of training

• Fat Mass (%)

  The subjects underwent a set of anthropometric assessments, which followed the norms of the International Society for Advancement of Kinanthropometry. The fat mass was calculated by percentage using the equation proposed by Jackson and Pollock (1978) from seven skinfold measurement. To measure the skinfolds, a Sanny Professional Skinfold Caliper was used.

  Pre and post 14 weeks/46 sessions of training

Secondary Outcomes (4)

• Heart Rate on Submaximal Test

  Pre; during (retest I 0-6weeks; retest II 0-10 weeks) and post 14 weeks/46sessions training: rest (5-min sitting; before start the test); maximal during the test (maxHRsub); 60s-120s immediately after the end of the test (on sitting position).

• Blood Lactate on Submaximal Test

  Pre; during (retest I 0-6weeks; retest II 0-10 weeks) and post 14 weeks/46 sessions training: rest (5-min sitting; before start the test); 1-3-5 minutes immediately after the end of the test (on sitting position).

• Submaximal Velocity [Vsub]

  Pre; during (retest I 0-6weeks; retest II 0-10 weeks) and post 14 weeks/46sessions of training

• Rate of Perceived Exertion (RPE) on Submaximal Test

  Pre; during (retest I 0-6weeks; retest II 0-10 weeks) and post 14 weeks/46sessions training

Study Arms (3)

interval

EXPERIMENTAL

The running training for interval group were performed on a treadmill for a period of 14 weeks, with a frequency of three times a week, lasting 20-minutes per session thus completing 46 sessions of training. The intensity and volume of training both were adapted according to the recommendations of the American College of Sports Medicine. The interval training group intensities ranged between 84-87% of maximal heart rate (HRmax) (vigorous intensity), 88-93%HRmax (near maximum intensity) and 94-99% HRmax (maximum intensity).

Other: running training

continuous

EXPERIMENTAL

The running training for continuous group were performed on a treadmill for a period of 14 weeks, with a frequency of three times a week, lasting 20-minutes per session thus completing 46 sessions of training. The intensity and volume of training both were adapted according to the recommendations of the American College of Sports Medicine.The continuous group ran at an intensity of \~87% of maximal heart rate (HRmax)

Other: running training

control

NO INTERVENTION

The control group did not do the running training program. Control did their normal physical activities.

Interventions

running training OTHER

The present study was designed to compare the physiological effects between the two training regimes and the control group.The subjects from interval and continuous group performed others activities as resistance training, swimming or soccer. Those activities wasn't controlled by our study, but the individual didn't do physical activities at least 3 hours before started our running sessions. The control group simply performed their normal physical activities (resistance training, swimming or soccer). But, each 3 weeks we had a contact with control group to check about any injury or illness that could affect the final results. None were found.

Also known as: Stochastic, aerobic, run

continuous; interval

Eligibility Criteria

• Age: 25 Years - 32 Years
• Sex: male
• Healthy Volunteers: No
• Age Groups: Adult (18-64)

You may qualify if:

• self reporting no contraindication to high-intensity exercise.
• physically active on cardiorespiratory activities in a regular basis for at least six months.
• presence of negative responses on all items of the Questionnaire of Physical Activity Readiness (PAR-Q Test).

You may not qualify if:

• make use of medication that may interfere with the results, especially inhibitors appetites and dietary supplements.
• presence of joint problems that prevents the achievement of training.
• presence of disorders such as diabetes, dyslipidemia and anemia
• have performed intense exercise with lowers members before the training sessions.

Sponsors & Collaborators

• University of Trás-os-Montes and Alto Douro: lead

Study Sites (1)

CEFAN

Rio de Janeiro, Rio de Janeiro, 21012350, Brazil

Location

MeSH Terms

Interventions

Stochastic Processes; Jogging

Intervention Hierarchy (Ancestors)

Statistics as Topic; Epidemiologic Methods; Investigative Techniques; Mathematical Concepts; Health Care Evaluation Mechanisms; Quality of Health Care; Health Care Quality, Access, and Evaluation; Public Health; Environment and Public Health; Running; Locomotion; Movement; Musculoskeletal Physiological Phenomena; Musculoskeletal and Neural Physiological Phenomena; Exercise; Motor Activity

Results Point of Contact

• Title: Ph.D. Laura Castro de Garay
• Organization: University of Trás-os-Montes and Alto Douro

laura@virtualsoftware.com.br

+55 21 22275084

Study Officials

• Laura C Garay, Ph.D.

  University of Trás-os-Montes and Alto Douro

  PRINCIPAL INVESTIGATOR

Publication Agreements

• PI is Sponsor Employee: Yes
• Restrictive Agreement: No

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: BASIC SCIENCE
• Intervention Model: FACTORIAL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator

Study Record Dates

• First Submitted: March 14, 2013
• First Posted: March 22, 2013
• Study Start: March 1, 2012
• Primary Completion: August 1, 2012
• Study Completion: December 1, 2012
• Last Updated: April 29, 2014
• Results First Posted: January 14, 2014

Record last verified: 2014-04

Locations

BR (1)