Pericapsular Nerve Group With Lateral Femoral Cutaneous Nerve Block vs Suprainguinal Fascia Iliaca Block for Analgesia in Total Hip Arthroplasty: A Prospective Comparative Study

NCT06844162 | Completed

• 1 other identifier: KA-22088
• Study Type: observational
• Target: 48
• Locations: 1 country
• Sites: 1

Brief Summary

Prospective observational cohort comparing analgesic efficacy of suprainguinal fascia iliaca block (SFIB) vs pericapsular nerve group block combined with lateral femoral cutaneous nerve block (PENG+LFCN) in primary total hip arthroplasty under general anesthesia (n=48). Outcomes include VAS pain at rest and with movement at 3, 12, 24, 48 h; morphine use (0-3, 3-12, 12-24, 24-48 h; total 0-48 h); quadriceps strength at 6 and 24 h; physiotherapy participation at 24 and 48 h; and adverse events within 48 h.

Conditions

Coxarthrosis; Primary

Keywords

Suprainguinal fascia iliaca block; PENG block; Lateral femoral cutaneous nerve block; Postoperative analgesia

Outcome Measures

Primary Outcomes (1)

• Visual Analogue Scale scores

  Postoperative Visual Analogue Scale scores ( Minimum of 0 and maximum of 10 with higher scores indicative of more severe pain) will be measured at rest and 45 degrees passive flexion at 3, 12, 24 and 48th hours postoperatively

  In the 48 hours following surgery

Secondary Outcomes (3)

• Opioid consumption

  In the 48 hours following surgery

• Quadriceps weakness

  In the 48 hours following surgery

• Ability to perform physiotherapy

  In the 48 hours following surgery

Other Outcomes (1)

• Adverse effects

  In the 48 hours following surgery

Study Arms (2)

SFIB

Patients undergoing THA who received ultrasound-guided SFIB with 0.25% bupivacaine 40 mL under the fascia iliaca with cranial spread.

PENG

Patients undergoing THA who received ultrasound-guided PENG (0.5% bupivacaine 15 mL) at the iliopubic eminence plus LFCN block (0.5% bupivacaine 5 mL) distal to the inguinal ligament.

Eligibility Criteria

• Age: 18 Years - 90 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

48 patients of American Society of Anesthesiologists physical status I-II between the age of 18 to 90 years who were scheduled to undergo primary Total hip arthroplasty with a diagnosis of coxarthrosis

You may qualify if:

• Patients who are scheduled to undergo primary total hip arthroplasty with a diagnosis of coxarthosis

You may not qualify if:

• Patients who have a history of neuropathy, patients with renal and hepatic insufficiency, patients with known coagulopathy, patients with a history of allergy to local anesthetics, patients with a history of inguinal surgery on the same side and patients with impaired mental status

Sponsors & Collaborators

• Hacettepe University: lead

Study Sites (1)

Hacettepe University Hospitals

Ankara, 06230, Turkey (Türkiye)

Location

MeSH Terms

Conditions

Osteoarthritis, Hip

Condition Hierarchy (Ancestors)

Osteoarthritis; Arthritis; Joint Diseases; Musculoskeletal Diseases; Rheumatic Diseases

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Lecturer

Study Record Dates

• First Submitted: February 19, 2025
• First Posted: February 25, 2025
• Study Start: February 1, 2024
• Primary Completion: April 15, 2024
• Study Completion: April 15, 2024
• Last Updated: August 26, 2025

Record last verified: 2025-08

Data Sharing

• IPD Sharing: Will share

Locations

TU (1)