NCT05763368

Brief Summary

Disturbances of balance and postural stability are frequent in patients with coxarthrosis due to the damage to the mechanoreceptors, characteristic of arthritic degeneration, and muscular hypotrophy of the affected limb. The aim of the study is to evaluate with adequate instrumentation the alterations of proprioception and postural control in patients with hip osteoarthrosis and the effectiveness of joint reconstruction in improving any deficit.

Trial Health

30
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Timeline
Completed

Started Apr 2022

Typical duration for not_applicable

Geographic Reach
1 country

1 active site

Status
withdrawn

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

April 1, 2022

Completed
3 months until next milestone

First Submitted

Initial submission to the registry

July 14, 2022

Completed
8 months until next milestone

First Posted

Study publicly available on registry

March 10, 2023

Completed
22 days until next milestone

Primary Completion

Last participant's last visit for primary outcome

April 1, 2023

Completed
1 year until next milestone

Study Completion

Last participant's last visit for all outcomes

April 1, 2024

Completed
Last Updated

May 25, 2023

Status Verified

May 1, 2023

Enrollment Period

1 year

First QC Date

July 14, 2022

Last Update Submit

May 23, 2023

Conditions

Outcome Measures

Primary Outcomes (2)

  • Change from baseline postural stability and proprioception

    Improvement of stability, evaluated with Berg Balance Scale, 0=minimum (the worst), 56 = maximum (the best)

    At baseline, 3 months, 6 months, and 12 months from surgery

  • Change from baseline postural stability and proprioception

    Improvement of stability and proprioception, evaluated with Delos Proprioceptive System

    At baseline, 3 months, 6 months, and 12 months from surgery

Secondary Outcomes (3)

  • Clinical improvements

    At baseline, 3 months, 6 months, and 12 months from surgery

  • Clinical improvements

    At baseline, 3 months, 6 months, and 12 months from surgery

  • Patient satisfaction

    At baseline, 3 months, 6 months, and 12 months from surgery

Study Arms (2)

Minimally Invasive Lateral Approach

ACTIVE COMPARATOR
Diagnostic Test: Clinical tests and proprioception evaluation

Anterior Approach

ACTIVE COMPARATOR
Diagnostic Test: Clinical tests and proprioception evaluation

Interventions

Each patient will be evaluated using clinical scales (BBS, HHS, HOOS, SF12) and ''Delos Proprioceptive System'' to assess postural stability and proprioception.

Anterior ApproachMinimally Invasive Lateral Approach

Eligibility Criteria

Age45 Years - 65 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Primary Osteoarthrosis
  • BMI \< 35 kg/m\^2
  • Able to stand in monopodalic support without aids / support

You may not qualify if:

  • History of previous hip or knee replacement
  • Orthopedic trauma within the previous 6 months
  • Pathologies that can interfere with balance: neurological (of the central nervous system, neuropathies, movement disorders), vestibular, visual, cognitive disability, consumption of alcohol / drugs / psychoactive drugs in the 24 hours prior to the test

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

IRCCS-Istituto Ortopedico Rizzoli

Bologna, 40136, Italy

Location

MeSH Terms

Conditions

Osteoarthritis, Hip

Condition Hierarchy (Ancestors)

OsteoarthritisArthritisJoint DiseasesMusculoskeletal DiseasesRheumatic Diseases
0

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NON RANDOMIZED
Masking
NONE
Purpose
SCREENING
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Rehabilitation Unit Head

Study Record Dates

First Submitted

July 14, 2022

First Posted

March 10, 2023

Study Start

April 1, 2022

Primary Completion

April 1, 2023

Study Completion

April 1, 2024

Last Updated

May 25, 2023

Record last verified: 2023-05

Locations