The Development of Diagnosis and Prognosis Predictive Model for Peripheral Nerve Disease

NCT06843642 | Completed

• 1 other identifier: 2025-0015-01
• Study Type: observational
• Target: 10,000
• Locations: 1 country
• Sites: 1

Brief Summary

This is a retrospective observational cohort study (MRN-PND), aiming to explore the utility of contrast-enhanced MRN (ceMRN) compared to plain MRN in diagnosing peripheral nerve diseases and predicting the prognosis of patients with these conditions. Additionally, artificial intelligence (AI) methods are employed to enhance the diagnostic accuracy of MRN for peripheral nerve diseases and to precisely predict disease outcomes.

Conditions

Peripheral Nerve Disease

Outcome Measures

Primary Outcomes (1)

• Correlation analysis of MR information and diagnosis outcome

  The indicator is the area under the curve of the predict diagnosis outcome.

  0.5 year

Study Arms (2)

Healthy Volunteers

Patients with Peripheral Nerve Disease

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Healthy People and Patients with Peripheral Nerve Disease

You may qualify if:

• Patients who underwent MRN scanning at Wuhan Union Hospital between January 2015 and January 2025;
• Age \> 18 years;
• Definitive clinical diagnosis (either healthy individuals or patients with a specific condition).

You may not qualify if:

• Poor quality of imaging;
• Incomplete clinical data or loss to follow-up;
• Unclear clinical diagnosis.

Sponsors & Collaborators

• Union Hospital, Tongji Medical College, Huazhong University of Science and Technology: lead
• Wuhan No.1 Hospital: collaborator
• University Hospital Heidelberg: collaborator
• West China Hospital: collaborator

Study Sites (1)

Union Hospital，Tongji Medical College，Huazhong University of Science and Technology

Wuhan, Hubei, 430000, China

Location

MeSH Terms

Conditions

Peripheral Nervous System Diseases

Condition Hierarchy (Ancestors)

Neuromuscular Diseases; Nervous System Diseases

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: February 12, 2025
• First Posted: February 25, 2025
• Study Start: January 1, 2015
• Primary Completion: January 1, 2025
• Study Completion: January 1, 2025
• Last Updated: February 25, 2025

Record last verified: 2025-02

Locations

CN (1)