Comparison of Sub-maximal Voluntary Isometric Training vs Eccentric Training in Management of De Quervain Tenosynovitis

NCT06839690 | Recruiting

• 1 other identifier: FUI/CTR/2025/1
• Study Type: interventional
• Target: 58
• Locations: 1 country
• Sites: 1

Brief Summary

This study is a randomised control trial and the purpose of this study is to compare the effects of Sub-maximal Voluntary Isometric Training vs Eccentric Training in Management of De Quervain Tenosynovitis

Conditions

De Quervain Syndrome

Outcome Measures

Primary Outcomes (1)

• Grip Strength measurement

  Power grip strength will be measured using hand held dynamometer and pinch grip strength will be measured using Modified sphygmomanometer

  4 weeks

Study Arms (2)

Sub-maximal Voluntary Isometric training Group

ACTIVE COMPARATOR

Group A will recieve ultrasound therapy for symptoms management and isometric training of thumb muscles (abducttor pollices longus and extensor pollices brevis) to gain improvement in range of motion and strength

Procedure: Isometric training of thumb muscles; Procedure: Ultrasound

Eccentric training Group

EXPERIMENTAL

Group B will receive the ultrasound therapy similar to group A for symptoms management and eccentric training of thumb muscles to gain improvement in range of motion and strength of thumb

Procedure: Eccentric training for thumb muscles; Procedure: Ultrasound

Interventions

Isometric training of thumb muscles PROCEDURE

Isometric training for thumb extension, abduction, radial and ulnar deviation will be performed in 3 sessions/ week for 4 weeks. The exercise protocol will begin with training using manual resistance and progress with training against resistance of elastic band and theraband.I

Sub-maximal Voluntary Isometric training Group

Eccentric training for thumb muscles PROCEDURE

In Group B, eccentric training for thumb extension, abduction, radial and ulnar deviation will be performed in 3 sessions/ week for 4 weeks. The exercise protocol will begin with training using unweighted and weighted hammer curls and progress with training using elastic band, dumbbell and theraband.

Eccentric training Group

Ultrasound PROCEDURE

Therapeutic ultrasound for symptom management

Eccentric training Group; Sub-maximal Voluntary Isometric training Group

Eligibility Criteria

• Age: 21 Years - 50 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64)

You may qualify if:

• Patients having history of pain, tenderness in thumb region from 3 weeks or more
• Age 21-50
• Both genders
• Individuals meeting the diagnostic criteria i.e.
• A score of 3 or more out of 7 on De Quervain screening tool.
• Positive Wrist hyperflexion and abduction of thumb (WHAT) test
• Positive Finkelstein's / Eichhoff's test

You may not qualify if:

• Diagnosed cases of Osteoarthritis of 1st CMC joint and Rheumatoid arthritis
• C6 cervical radiculopathy
• Any systemic inflammatory condition like septic arthritis
• Carpal Tunnel Syndrome
• Complex regional pain syndrome
• Previous surgery impacting the first extensor compartment of the wrist
• Corticosteroid injection in the radial wrist region within 3 months of enrolment into the study
• If patient had undergone isometric thumb exercises or any strengthening protocol lasting greater than 2 weeks for the management of their current episode of de Quervain's syndrome

Sponsors & Collaborators

• Foundation University Islamabad: lead

Study Sites (1)

Foundation University College of Physcial Therapy

Rawalpindi, Punjab Province, 46000, Pakistan

RECRUITING

MeSH Terms

Interventions

High-Energy Shock Waves

Intervention Hierarchy (Ancestors)

Ultrasonic Waves; Sound; Radiation, Nonionizing; Radiation; Physical Phenomena

Central Study Contacts

Zahra Nayyer, MS-MSKPT*

CONTACT

0349-8219386; zahranayyar727@gmail.com

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Model Details: Randomized Control Trial

Study Record Dates

• First Submitted: February 17, 2025
• First Posted: February 21, 2025
• Study Start: July 18, 2024
• Primary Completion: June 1, 2025
• Study Completion: June 20, 2025
• Last Updated: February 21, 2025

Record last verified: 2025-02

Locations

PA (1)