Association Between Preoperative Anxiety and Blood Eosinophil Levels

NCT06837415 | Enrolling By Invitation

• 1 other identifier: KAEK/2019.04.98
• Study Type: observational
• Target: 400
• Locations: 1 country
• Sites: 1

Brief Summary

In the studies, the presence of preoperative anxiety has been evaluated and reported with anxiety scales. The presence of anxiety and allergic diseases has also been examined in a limited study with the analysis of neuroendocrine cells. In this study, it was planned to support the eosinophilia response in peripheral blood accelerated by stress-related anxiety with anxiety scales. In patients who apply to the anesthesia clinic before surgery, the preoperative anxiety level will be measured with the STAIT(The State-Trait Anxiety Inventory Test) and APAIS (The Amsterdam Preoperative Anxiety and Information Scale) scales performed before the anesthesia evaluation and the relationship with the eosinophil count in the patient's complete blood count analysis will be evaluated.

Conditions

Preoperative Anxiety; Preoperative Evaluation; STAI; Eosinophil Blood Count

Outcome Measures

Primary Outcomes (1)

• Correlation between blood eosinophil count and preoperative anxiety

  1 day (From enrollment to the end of completion of the survey forms)

Study Arms (2)

Arm control

Arm eosinophilia

Eligibility Criteria

• Age: 16 Years - 85 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

The study will be conducted on patients aged 16-85 years who apply for preoperative anesthesia evaluation for an elective surgical procedure by an anesthesiologist at the Health Sciences University Kanuni Sultan Süleyman E.A.H. Anesthesia Polyclinic.

You may qualify if:

• scheduled for elective surgery
• Have sufficient language skills for the interview
• Ages 16-85
• ASA I - III
• Patients who apply to the anesthesia clinic for anesthesia evaluation

You may not qualify if:

• under the age of 16
• Patients who do not consent
• Patients with insufficient language skills
• Patients with mental and/or psychiatric disorders
• Patients with a history of emergency and/or ASA-IV
• sedative drug use

Sponsors & Collaborators

• Naime Yalçın: lead

Study Sites (1)

Sağlık Bilimleri Üniversitesi Kanuni Sultan Süleyman Eğitim ve Araştırma Hastanesi

Istanbul, 34000, Turkey (Türkiye)

Location

Biospecimen

Retention: SAMPLES WITH DNA

complete blood count, blood eosinophil count

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Target Duration: 1 Day
• Sponsor Type: OTHER
• Responsible Party: SPONSOR INVESTIGATOR
• PI Title: Specialist Anesthesiology and Reanimation, Principal Investigator

Study Record Dates

• First Submitted: February 16, 2025
• First Posted: February 20, 2025
• Study Start: May 1, 2019
• Primary Completion: September 1, 2025
• Study Completion: November 1, 2025
• Last Updated: February 21, 2025

Record last verified: 2025-02

Locations

TU (1)