Calf Circumference Adjusted for Body Composition to Assess Muscle Mass
1 other identifier
observational
150
0 countries
N/A
Brief Summary
Muscle mass is a critical indicator for malnutrition and sarcopenia assessment. Anthropometric measurements like calf circumference (CC) could be a simple and cost-effective alternative when gold standard methods are not available. However, CC is probably less accurate for estimating muscle mass in female patients and patients with obesity. This study investigates whether adjusting CC using mid-upper arm circumference (MUAC) improves muscle mass estimation in patients with obesity. If validated, this correction method would serve as a simple clinical tool for muscle mass assessment.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P50-P75 for all trials
Started Feb 2025
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
February 4, 2025
CompletedStudy Start
First participant enrolled
February 15, 2025
CompletedFirst Posted
Study publicly available on registry
February 17, 2025
CompletedPrimary Completion
Last participant's last visit for primary outcome
June 30, 2025
CompletedStudy Completion
Last participant's last visit for all outcomes
June 30, 2026
ExpectedFebruary 17, 2025
February 1, 2025
5 months
February 4, 2025
February 10, 2025
Conditions
Outcome Measures
Primary Outcomes (1)
Accuracy of corrected calf circumference in estimating muscle mass
Accuracy of corrected calf circumference in estimating muscle mass in comparison to densitometry (DEXA) used as a gold standard
15 months
Secondary Outcomes (4)
Comparison of accuracy of corrected calf measurement results in female patients
15 months
Comparison of accuracy of corrected calf measurement results in obese patients
15 months
Quality of life with and without corrected results of anthropometry
15 months
Bone density estimated from corrected calf circumference
15 months
Study Arms (1)
Patients undergoing bone density scanning at Tartu University Hospital
Patients undergoing bone density scanning at Tartu University Hospital selected from those attending the internal medicine clinics
Eligibility Criteria
Patients of the internal medicine clinic for whom diagnostic bone density scanning (DEXA) has been requested by the physician normally responsible for the patient's care
You may qualify if:
- Booked to undergo bone density scanning (DEXA) at Tartu University Hospital
You may not qualify if:
- Isolation for infectious disease Pregnancy and lactation Unable to understand or follow study protocol
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Related Publications (1)
Deutz NEP, Ashurst I, Ballesteros MD, Bear DE, Cruz-Jentoft AJ, Genton L, Landi F, Laviano A, Norman K, Prado CM. The Underappreciated Role of Low Muscle Mass in the Management of Malnutrition. J Am Med Dir Assoc. 2019 Jan;20(1):22-27. doi: 10.1016/j.jamda.2018.11.021.
PMID: 30580819BACKGROUND
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- STUDY DIRECTOR
Alastair Forbes, MD
University of Tartu
Central Study Contacts
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Visiting Professor
Study Record Dates
First Submitted
February 4, 2025
First Posted
February 17, 2025
Study Start
February 15, 2025
Primary Completion
June 30, 2025
Study Completion (Estimated)
June 30, 2026
Last Updated
February 17, 2025
Record last verified: 2025-02