Functional Recovery After Total Knee Arthroplasty
1 other identifier
observational
30
1 country
1
Brief Summary
The goal of this observational study is to learn about patients' recoveries after receiving total knee arthroplasty (TKA). The main questions it aims to answer are: Does robotic-assisted TKA have improved perceived recovery when compared to conventional TKA? Does robotic-assisted TKA lead to improved functional recovery when compared to conventional TKA? Researchers will compare if robotic-assisted versus conventional procedures lead to different recovery speeds. Participants will answer questionnaires and undergo physical therapy testing before and at several timepoints after their procedure.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at below P25 for all trials
Started Sep 2023
Typical duration for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
September 1, 2023
CompletedFirst Submitted
Initial submission to the registry
February 6, 2025
CompletedFirst Posted
Study publicly available on registry
February 11, 2025
CompletedPrimary Completion
Last participant's last visit for primary outcome
May 1, 2026
CompletedStudy Completion
Last participant's last visit for all outcomes
May 1, 2027
ExpectedDecember 11, 2025
December 1, 2025
2.7 years
February 6, 2025
December 4, 2025
Conditions
Outcome Measures
Primary Outcomes (5)
Timed Up and Go (TUG)
TUG requires the patient to sit in a chair, stand, walk to a line 3m away, turn, walk back to the chair, and sit again
anytime pre-operatively (baseline) and 2 weeks, 6 weeks, 3 months, 6 months, and 1 year post surgery
4m and 10m Walking Speed Test
anytime pre-operatively (baseline) and 2 weeks, 6 weeks, 3 months, 6 months, and 1 year post surgery
2-minute Walk
anytime pre-operatively (baseline) and 2 weeks, 6 weeks, 3 months, 6 months, and 1 year post surgery
Stair Climb Test
anytime pre-operatively (baseline) and 2 weeks, 6 weeks, 3 months, 6 months, and 1 year post surgery
Y Balance Test
The YBT requires the person to balance on one leg whilst simultaneously reaching as far as possible with the other leg in three separate directions: anterior, posterolateral, and posteromedial
anytime pre-operatively (baseline) and 2 weeks, 6 weeks, 3 months, 6 months, and 1 year post surgery
Secondary Outcomes (4)
Forgotten Joint Score
anytime pre-operatively (baseline) and 2 weeks, 6 weeks, 3 months, 6 months, and 1 year post surgery
Promis
anytime pre-operatively (baseline) and 2 weeks, 6 weeks, 3 months, 6 months, and 1 year post surgery
SF36
anytime pre-operatively (baseline) and 2 weeks, 6 weeks, 3 months, 6 months, and 1 year post surgery
KOOS
anytime pre-operatively (baseline) and 2 weeks, 6 weeks, 3 months, 6 months, and 1 year post surgery
Study Arms (4)
Manual Revision TKA
These patients underwent revision TKA done manually
Robotic-assisted Revision TKA
These patients underwent revision TKA with robotic-assistance
Manual Primary TKA
These patients received primary TKAs done manually
Robotic-assisted Primary TKA
These patients received primary TKAs with robotic-assistance
Interventions
Total knee arthroplasty with robotic assisatance
Revision total knee arthroplasty without robotic assistance
Total knee arthroplasty without robotic assistance
Revision total knee arthroplasty with robotic assistance
Eligibility Criteria
The study population consists of patients who are candidates for primary or revision total knee arthroplasty.
You may qualify if:
- Candidate for TKA
- Speak English / understand study instructions--this is necessary to reliably complete the study questionnaires and understand study instructions which are not validated in other languages
- Have medical clearance from PCP, PI, or co-Investigator to participate in the study
- Willing to comply with all study procedures and be available for the duration of the study
You may not qualify if:
- + falls in the past year
- Unable to ambulate 100 ft without assistive device or rest period
- Acute illness
- Have a history of cardiovascular disease or hypertension not controlled by medication
- Severe visual impairment
- Lower-extremity amputation
- Neurological, muscular, systemic, or connective tissue disorder affecting the function of the lower extremities
- Pregnant
- Terminal illness
- Plans to have another joint replacement during study period
- Plans to relocate from immediate area during study period
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
University of Pittsburgh
Pittsburgh, Pennsylvania, 15213, United States
Study Officials
- PRINCIPAL INVESTIGATOR
Kenneth Urish, MD PhD
University of Pittsburgh
Central Study Contacts
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Associate Professor
Study Record Dates
First Submitted
February 6, 2025
First Posted
February 11, 2025
Study Start
September 1, 2023
Primary Completion
May 1, 2026
Study Completion (Estimated)
May 1, 2027
Last Updated
December 11, 2025
Record last verified: 2025-12
Data Sharing
- IPD Sharing
- Will not share