NCT06819813

Brief Summary

The aim of this project is to pilot test a novel mobile app intervention for adolescents with dysregulated eating behaviors and elevated weight status. This intervention will incorporate evidence-informed strategies targeting self-regulation into cognitive-behavioral treatment for maladaptive eating. Adolescents will use the app for 16 weeks and provide feedback on its usability and effectiveness in managing dysregulated eating.

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
50

participants targeted

Target at P25-P50 for not_applicable obesity

Timeline
13mo left

Started Jul 2025

Geographic Reach
1 country

2 active sites

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress44%
Jul 2025May 2027

First Submitted

Initial submission to the registry

January 28, 2025

Completed
14 days until next milestone

First Posted

Study publicly available on registry

February 11, 2025

Completed
5 months until next milestone

Study Start

First participant enrolled

July 14, 2025

Completed
1.3 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

October 15, 2026

Expected
8 months until next milestone

Study Completion

Last participant's last visit for all outcomes

May 30, 2027

Last Updated

April 24, 2026

Status Verified

April 1, 2026

Enrollment Period

1.3 years

First QC Date

January 28, 2025

Last Update Submit

April 21, 2026

Conditions

Keywords

Mobile InterventionAdolescent

Outcome Measures

Primary Outcomes (4)

  • Usability of intervention

    Perceptions that the intervention is or would be useful, useable, and satisfactory will be measured by the System Usability Scale.

    Week 16

  • Acceptability of intervention

    Perceptions that the intervention is or would be useful, useable, and satisfactory will be measured by the Usefulness, Satisfaction, and Ease of use questionnaire (USE).

    Week 16

  • Body mass index percentile

    Adolescents will have their height and weight measured to calculate body mass index percentile using nationally representative growth charts and accompanying procedures. These data will be collected at each of the 4 major time points (pre-intervention assessment, mid-intervention assessment, post-intervention assessment, and 4-month follow up assessment).

    Through study completion (up to 9 months)

  • Dysregulated eating

    Dysregulated eating (overeating and loss of control eating episodes) will be measured using the Eating Disorder Examination (EDE; interview and questionnaire). The EDE features 4 subscales that are rated on a 7-point forced-choice format (0-6), with higher scores reflecting greater severity or frequency. These measures will be completed at each of the 4 major time points (pre-intervention assessment, mid-intervention assessment, post-intervention assessment, and 4-month follow up assessment).

    Through study completion (up to 9 months)

Other Outcomes (4)

  • Comorbid diagnoses

    Pre-intervention assessment

  • Intervention targets (activity patterns)

    Through study completion (up to 9 months)

  • Intervention targets (dietary patterns)

    Through study completion (up to 9 months)

  • +1 more other outcomes

Study Arms (1)

Feasibility/Efficacy Testing Participants

EXPERIMENTAL

All participants will all be assigned to the experimental group in this single-arm open trial.

Behavioral: Feasibility/Efficacy Testing

Interventions

This digital intervention will include elements of adapted cognitive-behavioral treatment for adolescent binge eating and weight control, with a focus on self-regulation and skills use.

Feasibility/Efficacy Testing Participants

Eligibility Criteria

Age13 Years - 19 Years
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64)

You may qualify if:

  • BMI≥75th percentile for their age and sex
  • Report recent loss of control eating and/or overeating (≥3 episodes of either type of eating behavior in the past 3 months)
  • Have an email address, Smartphone, and regular access to the internet
  • Be willing and able to measure their height and weight prior to study enrollment

You may not qualify if:

  • Report more than 2 instances of compensatory behavior (e.g. diuretics, laxatives, vomiting, driven exercise) in the past 3 months
  • Not fluent in English at a third-grade reading level or higher
  • Currently taking medications known to affect weight or appetite or concurrently involved in treatment for eating or weight disorders
  • Meet criteria for a medical or psychiatric condition (e.g., diabetes, bulimia nervosa) known to significantly affect eating or weight, aside from binge eating disorder
  • Developmental or cognitive delay precluding participation in the intervention
  • Currently pregnant or lactating

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (2)

Northwestern University

Chicago, Illinois, 60208, United States

RECRUITING

University of Pittsburgh

Pittsburgh, Pennsylvania, 15213, United States

RECRUITING

Related Publications (1)

  • Goldschmidt AB, Ortega A, Rooper IR, Obleada KT, Chapa DAN, Silverberg B, Stalvey E, Camino MK, Levine MD, Yu L, Eichen DM, Graham AK. Virtual Intervention for Binge Eating (VIBE): Study protocol for a user-informed mobile intervention for dysregulated eating and weight gain prevention in adolescents. Contemp Clin Trials. 2026 Feb;161:108192. doi: 10.1016/j.cct.2025.108192. Epub 2025 Dec 18.

MeSH Terms

Conditions

ObesityBinge-Eating DisorderBulimia

Condition Hierarchy (Ancestors)

OverweightOvernutritionNutrition DisordersNutritional and Metabolic DiseasesBody WeightSigns and SymptomsPathological Conditions, Signs and SymptomsFeeding and Eating DisordersMental DisordersHyperphagiaSigns and Symptoms, Digestive

Study Officials

  • Andrea B Goldschmidt, Ph.D.

    University of Pittsburgh

    PRINCIPAL INVESTIGATOR
  • Andrea K Graham, Ph.D.

    Northwestern University

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Erin R Stalvey, MPH

CONTACT

Andrew Tyler, BS

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
TREATMENT
Intervention Model
SINGLE GROUP
Model Details: Open trial
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Associate Professor of Psychiatry

Study Record Dates

First Submitted

January 28, 2025

First Posted

February 11, 2025

Study Start

July 14, 2025

Primary Completion (Estimated)

October 15, 2026

Study Completion (Estimated)

May 30, 2027

Last Updated

April 24, 2026

Record last verified: 2026-04

Data Sharing

IPD Sharing
Will share

Research data from participants may be shared with the broader scientific community after publication. We will make data and documentation available only under a data-sharing agreement that provides for a commitment to: (1) use the data for research purposes only; (2) secure the data using appropriate computer technology; (3) destroy or return the data after analyses are completed; and (4) not attempt to identify participants individually. Information shared with outside collaborators will link personal health information to a unique study ID in order to maintain participant anonymity.

Shared Documents
STUDY PROTOCOL, SAP, ICF

Locations