The Effect of Coconut Oil on Alopecia

NCT06818370 | Recruiting

• 1 other identifier: Ankara Onkoloji EAH
• Study Type: interventional
• Target: 86
• Locations: 1 country
• Sites: 1

Brief Summary

İn this study will be conducted to evaluate the effect of coconut oil on alopecia in 86 female breast cancer patients treated at Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital between 01.02.2025-31.12.2025.

Conditions

Breast Cancer

Keywords

Alopecia; Breast Cancer; Coconut Oil

Outcome Measures

Primary Outcomes (1)

• National Cancer Instute (NCI) Common Terminology Criteria for Adverse Events (CTCAE); Alopecia

  Grade 1; Hair loss of \<50% of normal for that individual that is not obvious from a distance but only on close inspection; a different hair style may be required to cover the hair loss but it does not require a wig or hair piece to camouflage Grade 2; Hair loss of \>=50% normal for that individual that is readily apparent to others; a wig or hair piece is necessary if the patient desires to completely camouflage the hair loss; associated with psychosocial impact

  1-12 WEEK

Study Arms (2)

Experimental group

EXPERIMENTAL

At the beginning of the study,patients will be asked to fill out an individual information form containing demographic information and disease process before the first chemotherapy application.The coconut oil application protocol will be explained to the patients in the experimental group and 10 milliliters of coconut oil will be applied to the hair follicles once a week. Alopecia assessment will be done every week.

Other: Coconut Oil

Control Group

NO INTERVENTION

At the beginning of the study,patients will be asked to fill out an individual information form containing demographic information and disease process before the first chemotherapy application. Patients in the control group will be asked not to apply anything to their hair. In each subsequent week, the presence of hair loss of the patients will be evaluated with the alopecia evaluation scale.

Interventions

Coconut Oil OTHER

The coconut oil application protocol will be explained to the patients in the experimental group and 10 milliliters of coconut oil will be applied to the hair follicles once a week. Alopecia assessment will be done every week.

Experimental group

Eligibility Criteria

• Age: 18 Years - 65 Years
• Gender Eligibility Details: female
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• To have been diagnosed with breast cancer.
• The chemotherapy treatment plan should be planned as the Doxorubicin-Cyclophosphamide protocol.
• Volunteer to participate in the study.
• Be 18 years of age or older.
• Being a woman.

You may not qualify if:

• Having any health problem or disability that prevents communication (vision-hearing problems, neurological, psychiatric diseases).
• Planning other treatments other than the Doxorubicin-Cyclophosphamide protocol for the treatment of breast cancer.
• Not volunteering to participate in the study.
• Having previously experienced any disease/skin problem that causes hair loss.
• Having received chemotherapy before.

Sponsors & Collaborators

• Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital: lead
• Çankırı Karatekin University: collaborator

Study Sites (1)

Dr. Abdurrahman Yurtaslan Ankara Onkoloji Eğitim ve Araştırma Hastanesi

Ankara, Yenimahalle, 06170, Turkey (Türkiye)

RECRUITING

MeSH Terms

Conditions

Breast Neoplasms; Alopecia

Interventions

Coconut Oil

Condition Hierarchy (Ancestors)

Neoplasms by Site; Neoplasms; Breast Diseases; Skin Diseases; Skin and Connective Tissue Diseases; Hypotrichosis; Hair Diseases; Pathological Conditions, Anatomical; Pathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

Dietary Fats; Fats; Lipids; Plant Oils; Oils

Central Study Contacts

İsmail Dakdevir, Nurse

CONTACT

+905533228416; dakdevirismail@gmail.com

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: PARTICIPANT
• Masking Details: Patients with breast cancer in the experimental and control groups will be masked.
• Purpose: SUPPORTIVE CARE
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Nurse

Model Details: It will be conducted in a randomized controlled experimental design.

Study Record Dates

• First Submitted: February 5, 2025
• First Posted: February 10, 2025
• Study Start: February 3, 2025
• Primary Completion: December 31, 2025
• Study Completion: January 31, 2026
• Last Updated: February 12, 2025

Record last verified: 2025-02

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)