NCT06815263

Brief Summary

Listener training offers a promising avenue for improving communication for people with dysarthria due to Parkinson's disease by offsetting the intelligibility burden from the patient onto their primary communication partners. Here, we employ a repeated-measures, randomized controlled trial to establish the efficacy of listener training for patients with PD and their primary communication partners. This translational work will establish a new realm of clinical practice in which the intelligibility impairments in PD are addressed by training partners to better understand dysarthric speech, thus elevating communication outcomes and participation in daily life.

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
360

participants targeted

Target at P75+ for not_applicable

Timeline
37mo left

Started Apr 2025

Longer than P75 for not_applicable

Geographic Reach
1 country

2 active sites

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Progress27%
Apr 2025May 2029

First Submitted

Initial submission to the registry

February 3, 2025

Completed
4 days until next milestone

First Posted

Study publicly available on registry

February 7, 2025

Completed
2 months until next milestone

Study Start

First participant enrolled

April 7, 2025

Completed
3.7 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

January 1, 2029

Expected
4 months until next milestone

Study Completion

Last participant's last visit for all outcomes

May 1, 2029

Last Updated

April 23, 2026

Status Verified

April 1, 2026

Enrollment Period

3.7 years

First QC Date

February 3, 2025

Last Update Submit

April 22, 2026

Conditions

Dysarthria, Hypokinetic

Keywords

DysarthriaParkinson's diseaseSpeechListener

Outcome Measures

Primary Outcomes (1)

  • Speech intelligibility

    Percent words correct (PWC)

    pretest, during training, immediate posttest, one week posttest, one month posttest

Secondary Outcomes (3)

  • Listening effort

    Pretest, one week posttest, one month posttest

  • Comprehension

    Pretest, one week posttest, one month posttest

  • Communicative Participation Item Bank

    Pretest, one month posttest

Study Arms (2)

Experimental Condition

EXPERIMENTAL

Listener receives speech of patient with dysarthria

Behavioral: Listener Training

Control condition

SHAM COMPARATOR

Listener receives speech of speaker with no speech disorder

Behavioral: Listener Training

Interventions

Listener TrainingBEHAVIORAL

Partner participants are presented with individual audio phrases that make up passage reading speech stimuli and orthographic transcriptions of what the patient is saying. Partners are asked to listen carefully to the audio files and use the written subtitles to help them understand what is being said.

Control conditionExperimental Condition

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Primary language is English
  • years or older
  • medical diagnosis of Parkinson's disease (patient participants)
  • speech diagnosis of hyperkinetic dysarthria, exhibiting hallmark characteristics (patient participants)

You may not qualify if:

  • Severe cognitive impairment
  • Less than 18 years of age
  • Primary language other than English

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (2)

Florida State University

Tallahassee, Florida, 32306, United States

RECRUITING

Utah State University

Logan, Utah, 43221, United States

RECRUITING

MeSH Terms

Conditions

DysarthriaSpeech

Condition Hierarchy (Ancestors)

Articulation DisordersSpeech DisordersLanguage DisordersCommunication DisordersNeurobehavioral ManifestationsNeurologic ManifestationsNervous System DiseasesSigns and SymptomsPathological Conditions, Signs and SymptomsVerbal BehaviorCommunicationBehavior

Study Officials

  • Stephanie Borrie, PhD

    Utah State University

    PRINCIPAL INVESTIGATOR

  • Kaitlin Lansford, PhD

    Florida State University

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Morgan Robertson, PhD

CONTACT

435-797-1388morgan.robertson@usu.edu

Stephanie Borrie, PhD

CONTACT

435-797-1388stephanie.borrie@usu.edu

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
PARTICIPANT, OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

February 3, 2025

First Posted

February 7, 2025

Study Start

April 7, 2025

Primary Completion (Estimated)

January 1, 2029

Study Completion (Estimated)

May 1, 2029

Last Updated

April 23, 2026

Record last verified: 2026-04

Locations

US(2)