Effects of Resistance Exercise Compared to Whole-body Electromyostimulation in Young Female Dentists.

NCT06813092 | Completed

• 2 other identifiers: FeDeBoMa02UKER
• Study Type: interventional
• Target: 16
• Locations: 1 country
• Sites: 2

Brief Summary

Due to their high workload and unfavorable working position, young female dentists are particularly at risk of cardiometabolic diseases and an early reduction in bone mineral density (BMD). With focus on the latter issue, short bouts of resistance exercise with high strain magnitude and velocity are commonly considered to be a feasible option to prevent bone loss in the early years of young adulthood. In parallel, whole-body electromyostimulation (WB-EMS) a trainings technology able address all main muscle groups simultaneously, however with dedicated exercise intensity might be a time-effective, joint friendly and safe option to maintain BMD in people unable or unmotivated to exercise conventionally. In the present study, we aim to compare the effects of a single session of WB-EMS versus high intensity, high velocity resistance exercise on biomarkers of bone formation (Procollagen type 1 N propeptide, P1NP) and resorption (C-terminal telopeptide of type I collagen, CTX-I). We hypothesize that no clinically relevant different effects on P1NP and CTX-I were determined.

Conditions

Osteopenia; Cardiometabolic Conditions

Keywords

biomarkers; bone metabolism; exercise; whole-body electromyostimulation; female dentists

Outcome Measures

Primary Outcomes (1)

• Changes for C-terminal telopeptide of type I collagen from pre- to 15 min post-exercise

  Changes for C-terminal telopeptide of type I collagen (CTX-I) serum levels from pre- to 15 min post-exercise as determined by blood samples

  Immediately pre-exercise to 15 min post exercise of a single exercise session

Secondary Outcomes (3)

• Changes for Procollagen type 1 N propeptide from pre- to 15 min post-exercise

  Immediately pre-exercise to 15 min post exercise of a single exercise session

• Changes for resting glucose from pre- to 15 min post-exercise

  Immediately pr to 15 min post-exercise of a single exercise session

• Changes for hemoglobin A1c from pre- to 15 min post-exercise

  Immediately pre- to 15 min post-exercise of a single exercise session

Study Arms (2)

Whole-Body Electromyostimulation

EXPERIMENTAL

One single bout of whole-body electromyostimulation (20 min, bipolar, 85 Hz, 350 µs, rectangular, 6s of impulse, 4s of rest)

Other: Whole-Body Electromyostimulation

Resistance exercise

ACTIVE COMPARATOR

High intensity, high velocity resistance exercise (30 min, 5-6 exercises, 3 sets at 60-85% 1RM)

Other: Resistance exercise

Interventions

Whole-Body Electromyostimulation OTHER

20 min of WB-EMS (bipolar, 85 Hz, 350 µs, 6s impulse - 4s impulse break)

Whole-Body Electromyostimulation

Resistance exercise OTHER

High-intensity/high velocity multiple set resistance exercise

Resistance exercise

Eligibility Criteria

• Age: 18 Years - 30 Years
• Gender Eligibility Details: Female dentistry students and young dentists
• Healthy Volunteers: No
• Age Groups: Adult (18-64)

You may qualify if:

• female dental students (\>3rd semester) or licensed dentists
• no competitive sports background for \>2 years
• normal body mass (BMI\>18,5 and \<25 kg/m2)

You may not qualify if:

• more than one resistance exercise session per week (last 12 month)
• whole-body electromyostimulation during the last 12 month
• amenorrhea, oligomenorrhea

Sponsors & Collaborators

• University of Erlangen-Nürnberg Medical School: lead

Study Sites (2)

Institute of Radiology

Erlangen, 91052, Germany

Location

Institute of Radiology, University Hospital NErlangen

Erlangen, 91054, Germany

Location

Related Publications (1)

• Kemmler W, Bebenek M, von Stengel S, Bauer J. Peak-bone-mass development in young adults: effects of study program related levels of occupational and leisure time physical activity and exercise. A prospective 5-year study. Osteoporos Int. 2015 Feb;26(2):653-62. doi: 10.1007/s00198-014-2918-8. Epub 2014 Oct 7.

  PMID: 25288444 BACKGROUND

MeSH Terms

Conditions

Bone Diseases, Metabolic; Motor Activity

Interventions

Resistance Training

Condition Hierarchy (Ancestors)

Bone Diseases; Musculoskeletal Diseases; Metabolic Diseases; Nutritional and Metabolic Diseases; Behavior

Intervention Hierarchy (Ancestors)

Exercise Therapy; Rehabilitation; Aftercare; Continuity of Patient Care; Patient Care; Therapeutics; Physical Therapy Modalities; Physical Conditioning, Human; Exercise; Motor Activity; Movement; Musculoskeletal Physiological Phenomena; Musculoskeletal and Neural Physiological Phenomena

Study Officials

• Wolfgang Kemmler, PhD

  University Hospital Erlangen, Germany

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: OUTCOMES ASSESSOR
• Masking Details: Outcome assessor were not aware of the group status and were not allowed to ask correspondingly
• Purpose: OTHER
• Intervention Model: CROSSOVER
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Model Details: Randomized two-arm cross-over design

Study Record Dates

• First Submitted: February 3, 2025
• First Posted: February 6, 2025
• Study Start: March 15, 2025
• Primary Completion: July 15, 2025
• Study Completion: August 30, 2025
• Last Updated: January 30, 2026

Record last verified: 2025-06

Locations

DE (2)