Efficacy of Plyometrics to Increase Bone Mass in Men With Osteopenia

NCT00572104 | Completed DMC

• 2 other identifiers: 1095877R03AR055738
• Study Type: interventional
• Target: 38
• Locations: 1 country
• Sites: 1

Brief Summary

This study will compare the ability of two types of long term (12 months) weight-bearing exercise treatments (1. high-intensity jumping and 2. weight lifting) to increase bone mass of the total body, spine and hip in physically active men with osteopenia.

Conditions

Osteopenia

Outcome Measures

Primary Outcomes (1)

• Bone Mineral Density

  12 months

Secondary Outcomes (2)

• Serum markers of bone turnover

  3 months

• Serum hormones regulating bone turnover

  3 months

Study Arms (2)

resistance exercise

EXPERIMENTAL

12 month resistance exercise training

Other: resistance exercise

plyometric exercise

EXPERIMENTAL

12 month plyometric exercise training

Other: plyometric exercise

Interventions

resistance exercise OTHER

12 month training intervention of weight resistance exercise. All participants receive a daily calcium and vitamin D supplement

resistance exercise

plyometric exercise OTHER

12 month training intervention of plyometric exercise. All participants receive a daily calcium and vitamin D supplement

plyometric exercise

Eligibility Criteria

• Age: 25 Years - 60 Years
• Sex: male
• Healthy Volunteers: No
• Age Groups: Adult (18-64)

You may qualify if:

• Male
• Age 25-60 years
• No symptoms of disease
• Currently participating in cycling activities an average of 4 hr/wk for the previous 24 months
• Osteopenia of the lumbar spine and/or hip (T score \< -1.0 and \> -2.5 )

You may not qualify if:

• Medications or supplements that affect bone metabolism or prevent exercise
• Previous or current medical condition affecting bone health
• Osteoporosis of the lumbar spine and/or hip (T score \> -1.0 or \< -2.5)
• Cardiovascular disease
• Metallic implants
• Current smoker
• Current regular participation in high-intensity resistance training and/or plyometrics

Sponsors & Collaborators

• University of Missouri-Columbia: lead
• National Institutes of Health (NIH): collaborator
• National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS): collaborator

Study Sites (1)

University of Missouri-Columbia; McKee Gym

Columbia, Missouri, 65211, United States

Location

MeSH Terms

Conditions

Bone Diseases, Metabolic

Interventions

Resistance Training; Plyometric Exercise

Condition Hierarchy (Ancestors)

Bone Diseases; Musculoskeletal Diseases; Metabolic Diseases; Nutritional and Metabolic Diseases

Intervention Hierarchy (Ancestors)

Exercise Therapy; Rehabilitation; Aftercare; Continuity of Patient Care; Patient Care; Therapeutics; Physical Therapy Modalities; Physical Conditioning, Human; Exercise; Motor Activity; Movement; Musculoskeletal Physiological Phenomena; Musculoskeletal and Neural Physiological Phenomena

Study Officials

• Pamela S Hinton

  University of Missouri-Columbia, Department of Nutritional Sciences

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: December 10, 2007
• First Posted: December 12, 2007
• Study Start: January 1, 2008
• Primary Completion: November 1, 2013
• Study Completion: November 1, 2013
• Last Updated: October 7, 2016

Record last verified: 2016-10

Data Sharing

• IPD Sharing: Will not share

Locations

US (1)