The Effect of Different Exercise Approaches on Passive Mechanical Properties of Hamstring and Quadriceps Muscles, Strength and Jumping Performance
1 other identifier
interventional
40
1 country
1
Brief Summary
The mechanical characteristics play a crucial role in sustaining daily life activities and facilitating participation in sport activities and exercises demanding a diverse range of motion. Furthermore, it is postulated that the mechanical composition of the muscle could impact the minimal energy expenditure, perceived exertion, and risk of injury during physical activities. This study aims to examine the effects of various exercise approaches, including aerobic exercise, strength training, and whole-body vibration, on the passive mechanical properties of muscle tissue.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P25-P50 for not_applicable
Started Feb 2020
Typical duration for not_applicable
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
February 10, 2020
CompletedPrimary Completion
Last participant's last visit for primary outcome
August 15, 2021
CompletedStudy Completion
Last participant's last visit for all outcomes
January 5, 2022
CompletedFirst Submitted
Initial submission to the registry
January 26, 2025
CompletedFirst Posted
Study publicly available on registry
February 5, 2025
CompletedFebruary 5, 2025
January 1, 2025
1.5 years
January 26, 2025
January 30, 2025
Conditions
Keywords
Outcome Measures
Primary Outcomes (4)
Muscle Strength
Isokinetic testing and rehabilitation systems were utilized to assess muscle strength. An assessment was conducted on the concentric and eccentric forces exerted on the quadriceps femoris and hamstring muscles in the dominant lower extremity. The assessment of concentric strength was conducted within the knee flexion range of 0-90 degrees, while the evaluation of eccentric strength was undertaken in the knee flexion range of 10-90 degrees at a velocity of 60º/sec. The peak torque values acquired from the experiment were utilized as the basis for the analysis.
Baseline and at Week 4
Horizontal Jump
Test was conducted unilaterally on the dominant lower extremity. Horizontal jump was repeated three times and the average of the measurement results was recorded.
Baseline and at Week 4
Muscle Stiffness
Changes in muscle stiffness were evaluated through shear wave elastography. The alterations in the stiffness properties of the muscle were documented utilizing an ultrasound device. Measurements were conducted on the dominant lower extremity to evaluate alterations in the muscle stiffness of the quadriceps muscles (vastus medialis obliquus, rectus femoris) and hamstring muscles (biceps femoris, semimembranosus).
Baseline and at Week 4
Muscle Thickness
Changes in muscle thickness were evaluated through shear wave elastography. The alterations in the thickness properties of the muscle were documented utilizing an ultrasound device. Measurements were conducted on the dominant lower extremity to evaluate alterations in the muscle thickness of the quadriceps muscles (vastus medialis obliquus, rectus femoris) and hamstring muscles (biceps femoris, semimembranosus).
Baseline and at Week 4
Study Arms (4)
Whole Body Vibration Exercise
EXPERIMENTALWhole body vibration exercises were conducted utilizing a specialized exercise platform. The participants underwent a prescribed exercise protocol involving both static and dynamic exercises on the designated platform. Specifically, static squats at a 30º angle, dynamic deep squats ranging from 30 to 60º, toe raises, weight transfer maneuvers during squats, as well as static and dynamic squat exercises performed unilaterally were implemented as part of the program. Each exercise was performed for 30-50 s with a frequency ranging from 30-45 Hz and an amplitude of 2 mm. The exercise regimen was structured to comprise three sets, with a designated three-minute inter-set rest interval. Physical exercise sessions were conducted on a weekly basis, with a duration ranging from 30 to 45 minutes. The intensity and duration of the exercises were progressively adjusted based on the adherence.
Aerobic Exercise
EXPERIMENTALAerobic exercise group were directed to engage in running activity on a conventional treadmill. The participants engaged in aerobic exercise, specifically moderate-to-high-intensity running at 65-80% of their maximal heart rate, for durations of 30-45 minutes per session, three times weekly. Heart rate was monitored with a portable pulse oximetry device.
Strengthening Exercise
EXPERIMENTALStrengthening exercise group, participants engaged in various lower extremity strengthening activities such as straight leg raises, abduction and adduction movements, knee flexion-extension, ankle plantar-dorsiflexion exercises. These exercises were performed both on a bed and in standing positions, utilizing resistance exercise bands.
Control Group
NO INTERVENTIONThe participants continued their daily lives without any exercise practice until the end of the study.
Interventions
The participants underwent a prescribed exercise protocol involving both static and dynamic exercises on the designated platform. Specifically, static squats at a 30º angle, dynamic deep squats ranging from 30 to 60º, toe raises, weight transfer maneuvers during squats, as well as static and dynamic squat exercises performed unilaterally were implemented as part of the program
The participants assigned to the aerobic exercise group were directed to engage in running activity on a conventional treadmill. The participants engaged in aerobic exercise, specifically moderate-to-high-intensity running at 65-80% of their maximal heart rate, for durations of 30-45 minutes per session, three times weekly. Heart rate was monitored with a portable pulse oximetry device.
Strengthening group, participants engaged in various lower extremity strengthening activities such as straight leg raises, abduction and adduction movements, knee flexion-extension, ankle plantar-dorsiflexion exercises. These exercises were performed both on a bed and in standing positions, utilizing resistance exercise bands.
Eligibility Criteria
You may qualify if:
- Physically healthy and able to engage in the exercise program without any impediments.
- Voluntary participation
You may not qualify if:
- Prior surgical interventions.
- Neuromuscular or neurodegenerative disorders.
- Heart failure.
- Cardiac stents.
- Pregnancy.
- Participants who do not meet the above criteria, even if their current health status permits participation in exercise activities.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Bursa Uludag University
Bursa, Nilüfer, Turkey (Türkiye)
Related Publications (2)
Uysal O, Delioglu K, Firat T. The effects of hamstring training methods on muscle viscoelastic properties in healthy young individuals. Scand J Med Sci Sports. 2021 Feb;31(2):371-379. doi: 10.1111/sms.13856. Epub 2020 Nov 3.
PMID: 33084051BACKGROUNDBlazevich AJ. Adaptations in the passive mechanical properties of skeletal muscle to altered patterns of use. J Appl Physiol (1985). 2019 May 1;126(5):1483-1491. doi: 10.1152/japplphysiol.00700.2018. Epub 2018 Nov 9.
PMID: 30412028BACKGROUND
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- DOUBLE
- Who Masked
- PARTICIPANT, OUTCOMES ASSESSOR
- Purpose
- OTHER
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Doctor of Physical Therapy
Study Record Dates
First Submitted
January 26, 2025
First Posted
February 5, 2025
Study Start
February 10, 2020
Primary Completion
August 15, 2021
Study Completion
January 5, 2022
Last Updated
February 5, 2025
Record last verified: 2025-01