Adipokines in Polycystic Ovary Syndrome
Assessment of Adipokine Concentrations and Their Association With the Metabolic Profile of Women With PCOS
1 other identifier
observational
300
1 country
1
Brief Summary
The aim of the study is to compare the concentrations of leptin, resistin, and omentin-1 in women across three research groups: those with polycystic ovary syndrome without insulin resistance, those with polycystic ovary syndrome with insulin resistance, and women without polycystic ovary syndrome.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started Jan 2025
Typical duration for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
January 20, 2025
CompletedStudy Start
First participant enrolled
January 20, 2025
CompletedFirst Posted
Study publicly available on registry
January 27, 2025
CompletedPrimary Completion
Last participant's last visit for primary outcome
December 31, 2027
ExpectedStudy Completion
Last participant's last visit for all outcomes
December 31, 2027
March 18, 2026
March 1, 2026
2.9 years
January 20, 2025
March 17, 2026
Conditions
Keywords
Outcome Measures
Primary Outcomes (3)
Comparison of resistin concentration in three study groups
Measurement and comparison of mean fasting plasma resistin concentration expressed in pg/ml in three study groups
up to 6 months
Comparison of leptin concentration three study groups
Measurement and comparison of mean fasting plasma leptin concentration expressed in pg/ml in three study groups
up to 6 months
Comparison of omentin-1 concentration in three study groups
Measurement and comparison of mean fasting plasma omentin-1 concentration expressed in pg/ml in three study groups
up to 6 months
Study Arms (3)
PCOS+IR
Polycystic ovary syndrome + insulin resistance
PCOS + no IR
Polycystic ovary syndrome + no insulin resistance
No PCOS
Women without PCOS (control)
Interventions
Fasting plasma leptin concentration measurement with results expressed in pg/ml and comparison across all study arms
Fasting plasma resistin concentration measurement with results expressed in pg/ml and comparison across all study arms
Fasting plasma omentin-1 concentration measurement with results expressed in pg/ml and comparison across all study arms
Eligibility Criteria
women aged 18-45 years managed for menstrual irregularities or routine check-up
You may qualify if:
- Age 18-45
You may not qualify if:
- previous removal of at least one ovary
- treated diabetes of any type
- diagnosed and treated metabolic diseases
- diagnosed and treated autoimmune diseases
- diagnosed and treated autoinflammatory diseases(Edited)Restore original
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Jagiellonian Univeristy
Krakow, Poland
Biospecimen
blood serum
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- STUDY CHAIR
Kazimierz Pityński, Prof., Ph.D., M.D.
Jagiellonian University
Central Study Contacts
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- PhD, MD, Principal Investigator
Study Record Dates
First Submitted
January 20, 2025
First Posted
January 27, 2025
Study Start
January 20, 2025
Primary Completion (Estimated)
December 31, 2027
Study Completion (Estimated)
December 31, 2027
Last Updated
March 18, 2026
Record last verified: 2026-03