Validating the Ain Shams Cognitive Assessment Tool

NCT06789094 | Not Yet Recruiting DMC

• 1 other identifier: FMASU R310/2024
• Study Type: observational
• Target: 100
• Locations: 1 country
• Sites: 1

Brief Summary

The diagnosis of cognitive impairment, including dementia and mild cognitive impairment (MCI), is crucial for timely intervention and management. Various screening tools are available for assessing cognitive function, among which the Mini-Mental State Examination (MMSE), the Addenbrooke's Cognitive Examination (ACE), and the Montreal Cognitive Assessment (MoCA) are widely used. However, the recently developed Ain Shams University Cognitive Assessment (ASCA) has shown promise in detecting early cognitive decline. This study aims to assess the performance of ASCA in diagnosing cognitive impairment against DSM5 criteria.

Conditions

Mild Cognitive Impairment (MCI); Dementia

Keywords

Mild cognitive impairment; Dementia; cognitive assessment; Arabic cognitive assessment tools

Outcome Measures

Primary Outcomes (1)

• ASCA cut off points

  obtain cut-off scores for diagnosing mild cognitive impairment (MCI) and dementia using the Ain Shams Cognitive Assessment

  4 months

Study Arms (3)

Dementia

participants \>60 years with Dementia diagnosed by DSM-5 criteria

Other: Ain Shams University Cognitive Assessment (ASCA) tool

Mild cognitive impairment

participants \>60 years with Mild cognitive impairment (MCI) diagnosed by DSM-5 criteria

Other: Ain Shams University Cognitive Assessment (ASCA) tool

control

euthymic healthy community dwelling adult participants of various socioeconomic and educational status.

Other: Ain Shams University Cognitive Assessment (ASCA) tool

Interventions

Ain Shams University Cognitive Assessment (ASCA) tool OTHER

The ASCA, developed at Ain Shams University, is a comprehensive tool designed for cognitive assessment in Egyptian population. It encompasses various tests to assess cognitive functions and cultural understanding. These include the Verbal Paired Associated Test, evaluating verbal learning, distractor interval, delayed recall, and word recognition. The Bender Gestalt assesses visual-motor skills and memory. Short-term and working memory are tested through Digit Forward and Digit Backward Span Length tasks. Set Shifting is measured using a modified Trail Making Test, adapted for illiterates. Additionally, tests for letter/lexical fluency, verbal fluency, language object naming, abstraction, and judgment offer further insights into cognitive abilities and cultural interpretation.

Also known as: Patient Health Questionnaire 9, activity of daily living questionnaire

Dementia; Mild cognitive impairment; control

Eligibility Criteria

• Age: 60 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

Community dwelling elderly participants (caregivers of inpatients, attendants of primary care , elderly clubs and other community gatherings).

You may not qualify if:

• severe dementia, delirium, major mental disorders, aphasia, and those with severe visual or hearing impairment that interfere with the assessment.

Sponsors & Collaborators

• Ain Shams University: lead

Study Sites (1)

Ain Shams University

Cairo, Egypt

Location

MeSH Terms

Conditions

Cognitive Dysfunction; Dementia

Interventions

Equipment and Supplies; Patient Health Questionnaire

Condition Hierarchy (Ancestors)

Cognition Disorders; Neurocognitive Disorders; Mental Disorders; Brain Diseases; Central Nervous System Diseases; Nervous System Diseases

Intervention Hierarchy (Ancestors)

Surveys and Questionnaires; Data Collection; Epidemiologic Methods; Investigative Techniques; Psychological Tests; Behavioral Disciplines and Activities; Health Care Evaluation Mechanisms; Quality of Health Care; Health Care Quality, Access, and Evaluation; Public Health; Environment and Public Health

Central Study Contacts

Doha Rasheedy, Professor

CONTACT

01001193544; doharasheedy@med.asu.edu.eg

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Professor of Geriatrics and Gerontology

Study Record Dates

• First Submitted: January 17, 2025
• First Posted: January 23, 2025
• Study Start: February 1, 2025
• Primary Completion: May 1, 2025
• Study Completion: June 1, 2025
• Last Updated: January 23, 2025

Record last verified: 2025-01

Locations

EG (1)