Optimal Positive End-Expiratory Pressure in Robotic-Assisted Thoracic Surgery Without Capnothorax

NCT06784037 | Enrolling By Invitation

• 1 other identifier: HCB/2024/0103
• Study Type: observational
• Target: 60
• Locations: 1 country
• Sites: 1

Brief Summary

The aim of this study is to assess the impact on lung mechanics during robotic lung resection when no capnothorax is used.

Conditions

Robotic Thoracic Surgery; Mechanical Ventilation; Positive End Expiratory Pressure (PEEP)

Keywords

robotic lung surgery; PEEP; capnothorax

Outcome Measures

Primary Outcomes (3)

• Respiratory airway pressures

  Respiratory airway pressures (peak pressure, plateau pressure and PEEP in cmH2O)

  During intra-operative mechanical ventilation (4 hours)

• Respiratory rate

  Respiratory rate (in cycles per minute)

  During intra-operative mechanical ventilation (4 hours)

• Respiratory system compliance

  Respiratory pressures measurement will be combined to obtain respiratory system compliance. Respiratory system compliance = (plateau pressure-PEEP) / respiratory tidal volume (expressed in cmH2O/mL)

  During intra-operative mechanical ventilation (4 hours)

Secondary Outcomes (5)

• Arterial blood gas parameters: pO2

  During intra-operative mechanical ventilation (4 hours)

• Arterial blood gas parameters: pCO2

  During intra-operative mechanical ventilation (4 hours)

• Arterial blood gas parameters: pH

  During intra-operative mechanical ventilation (4 hours)

• Arterial blood gas parameters: sodium bicarbonate

  During intra-operative mechanical ventilation (4 hours)

• Arterial blood gas parameters: base excess

  During intra-operative mechanical ventilation (4 hours)

Study Arms (1)

URATS: Robotic lung surgery with no capnothorax

Uniportal robotic lung resection under no capnothorax

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Patients receiving uniportal robotic assisted lung resection with no capnothorax

You may qualify if:

• Patients undergoing uniportal robotic lung resection under no capnothorax

You may not qualify if:

• Refusal to participate
• Contraindications to recruitment maneuvers

Sponsors & Collaborators

• Hospital Clinic of Barcelona: lead

Study Sites (1)

Hospital Clinic Barcelona

Barcelona, Catalonia, 08036, Spain

Location

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Target Duration: 1 Month
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: December 16, 2024
• First Posted: January 20, 2025
• Study Start: February 16, 2024
• Primary Completion: December 31, 2025
• Study Completion: December 31, 2025
• Last Updated: January 20, 2025

Record last verified: 2024-12

Locations

ES (1)