Celiac Disease in Children

NCT06783673 | Completed

• 1 other identifier: Soh-Med--24-11-10MS
• Study Type: observational
• Target: 66
• Locations: 1 country
• Sites: 1

Brief Summary

The aim is to study the clinical, serological, endoscopic and histopathological characteristics and treatment outcome of children diagnosed with celiac disease in Sohag University Hospital

Conditions

Celiac Disease in Children

Keywords

clinicopathological, endoscopic and serological patterns of celiac disease in children

Outcome Measures

Primary Outcomes (1)

• Number of participants with Clinicopathological, endoscopic and serological patterns of Celiac disease

  clinical patterns of celiac disease include intestinal and extraintestinal manifestations. serological patterns include total IgA level, tissue transglutaminase IgA \& IgG levels and endomesial IgA \& IgG levels. Endoscopic patterns include patchy or generalized atrophy and scalloping of duodenal mucosa. Pathological patterns include features of mucosal atrophy and modified Marsh classification.

  1 Year

Study Arms (1)

patterns of celiac disease in children

clinicopathological, endoscopic and serological patterns of celiac disease in children

Procedure: Upper GIT endoscopy

Interventions

Upper GIT endoscopy PROCEDURE

upper GIT endoscopy of suspected cases and multiple biopsies will be taken for histopathological examination

Also known as: Upper endoscopy

patterns of celiac disease in children

Eligibility Criteria

• Age: 1 Year - 18 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64)
• Sampling Method: Non-Probability Sample

Study Population

The study will include children who will be admitted to the department of pediatrics at Sohag University Hospital during the study period and which will be fulfilling the following eligibility criteria in addition to all children previously diagnosed with celiac disease in the last 1 years.

You may qualify if:

• Children less than 18 years.
• Both sexes.
• Children suffering from manifestations of celiac disease.
• Children previously diagnosed with celiac disease.

You may not qualify if:

• cases more than 18 years.
• Children diagnosed with other causes of malabsorption

Sponsors & Collaborators

• Sohag University: lead

Study Sites (1)

Sohag University

Sohag, Sohag Governorate, 82524, Egypt

Location

MeSH Terms

Interventions

Gastroscopy

Intervention Hierarchy (Ancestors)

Endoscopy, Gastrointestinal; Endoscopy, Digestive System; Diagnostic Techniques, Digestive System; Diagnostic Techniques and Procedures; Diagnosis; Endoscopy; Diagnostic Techniques, Surgical; Digestive System Surgical Procedures; Surgical Procedures, Operative; Minimally Invasive Surgical Procedures

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: OTHER
• Target Duration: 6 Months
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: pediatrician

Study Record Dates

• First Submitted: December 30, 2024
• First Posted: January 20, 2025
• Study Start: August 25, 2024
• Primary Completion: March 3, 2025
• Study Completion: March 30, 2025
• Last Updated: April 9, 2025

Record last verified: 2025-04

Locations

EG (1)