Accuracy of FNAC in Diagnosis of Thyroid Nodules
1 other identifier
observational
100
0 countries
N/A
Brief Summary
Detection of degree of accuracy of FNAC in diagnosis of thyroid nodules
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P50-P75 for all trials
Started Mar 2025
Shorter than P25 for all trials
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
December 25, 2023
CompletedFirst Posted
Study publicly available on registry
January 20, 2025
CompletedStudy Start
First participant enrolled
March 1, 2025
CompletedPrimary Completion
Last participant's last visit for primary outcome
December 1, 2025
CompletedStudy Completion
Last participant's last visit for all outcomes
December 1, 2025
CompletedJanuary 20, 2025
December 1, 2024
9 months
December 25, 2023
January 17, 2025
Conditions
Outcome Measures
Primary Outcomes (4)
Incidence of true positive results of FNAC after thyroidectomy
Accuracy of FNAC in thyroid nodules compared to surgical specimen histopathological examination
12 days
Percentage of malignant thyroid nodules not observed by FNAC
Percentage of malignant thyroid nodules that FNAC fails to detect
12 days
Incidence of false negative results by FNAC
False negative that diagnosed by FNAC not malignant but proved malignancy after surgical excision
12 days
Percentage of total number of true results of FNAC to the total number of cases
Accuracy of FNAC
12 days
Interventions
observe results of FNAC and compare it with results of histopathological examination to detect accuracy of FNAC in diagnosis of thyroid nodules.
Eligibility Criteria
All patients presented to General Surgery Department with either solitary or multiple suspicious thyroid nodules during time of research.
You may qualify if:
- thyroid disease
- multinodular
- single nodule
- TIRAD 3 or more by US
- thyroid disease underwent FNAC then surgery
- all age groups
- patient fit for surgery
You may not qualify if:
- patients with comorbidities.
- patients unfit for surgery
- patients who refused surgery.
- Patient with no diagnostic FNAC.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Related Publications (3)
Poller DN, Stelow EB, Yiangou C. Thyroid FNAC cytology: can we do it better? Cytopathology. 2008 Feb;19(1):4-10. doi: 10.1111/j.1365-2303.2007.00492.x. Epub 2007 Oct 3.
PMID: 17916090BACKGROUNDBhise SV, Shaikh A, Hippargekar PM, Kothule S. A Prospective Study of Ultrasonographic and FNAC Correlation of Thyroid Swellings with Histopathology. Indian J Otolaryngol Head Neck Surg. 2022 Oct;74(Suppl 2):1942-1948. doi: 10.1007/s12070-020-01922-w. Epub 2020 Jun 24.
PMID: 36452634BACKGROUNDMomin MA, Bhuiyan FU, Chakraborty S, Kar NK. FNAC and Its Utility in Solitary Thyroid Nodule and Its Correlation with Histopathological Examination. Mymensingh Med J. 2019 Apr;28(2):356-363.
PMID: 31086151BACKGROUND
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Central Study Contacts
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Principal Investigator
Study Record Dates
First Submitted
December 25, 2023
First Posted
January 20, 2025
Study Start
March 1, 2025
Primary Completion
December 1, 2025
Study Completion
December 1, 2025
Last Updated
January 20, 2025
Record last verified: 2024-12
Data Sharing
- IPD Sharing
- Will not share