Elastography in Thyroid Nodules
Added Value of Ultrasound Elasatography in Characterization of Thyroid Nodules
1 other identifier
observational
50
0 countries
N/A
Brief Summary
Thyroid nodules are a common finding in the general population,however, they are mostly unpalpable and usually discovered either during neck ultrasound (US) examination or by pathological examination at autopsy. They are found in about 8% of adults. Most thyroid nodules ''incidentalomas" are benign, however 7% may be malignant. Early detection of thyroid cancer helps in early treatment and better survival US is an accurate method for detection of thyroid nodules; however, US has a low accuracy in differentiating between benign from malignant thyroid nodules . US could suggest a malignancy likelihood criteria of a thyroid nodule, such as hypoechogenicity, increased intranodular vascularity, irregular margins, microcalcifications, absent halo, and a taller-than-wide shape measured in the transverse dimension.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P25-P50 for all trials
Started Apr 2020
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
March 16, 2020
CompletedFirst Posted
Study publicly available on registry
March 18, 2020
CompletedStudy Start
First participant enrolled
April 1, 2020
CompletedPrimary Completion
Last participant's last visit for primary outcome
April 1, 2021
CompletedStudy Completion
Last participant's last visit for all outcomes
April 1, 2022
CompletedMarch 18, 2020
March 1, 2020
1 year
March 16, 2020
March 16, 2020
Conditions
Outcome Measures
Primary Outcomes (1)
To evaluate the role of Elastography in differentiation between benign and malignant thyroid nodules
by its additional information over the classic gray scale and color Doppler ultrasound
one year
Study Arms (1)
patients with thyroid nodules
Interventions
Eligibility Criteria
patients with solitary thyroid nodule
You may qualify if:
- solitary nodule on clinical or ultrasound examination
You may not qualify if:
- Patients received any medical treatment or chemo or radiotherapy.
- Patients underwent fine needle aspiration cytology or biopsy
- Nodules with calcification and cystic changes
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Related Publications (1)
Torre LA, Bray F, Siegel RL, Ferlay J, Lortet-Tieulent J, Jemal A. Global cancer statistics, 2012. CA Cancer J Clin. 2015 Mar;65(2):87-108. doi: 10.3322/caac.21262. Epub 2015 Feb 4.
PMID: 25651787BACKGROUND
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Study Design
- Study Type
- observational
- Observational Model
- CASE ONLY
- Time Perspective
- CROSS SECTIONAL
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- principal investigator
Study Record Dates
First Submitted
March 16, 2020
First Posted
March 18, 2020
Study Start
April 1, 2020
Primary Completion
April 1, 2021
Study Completion
April 1, 2022
Last Updated
March 18, 2020
Record last verified: 2020-03