Manage Your Workingnegative Thoughts Through Hypnosis

NCT06778109 | Completed

• 1 other identifier: IPNOSIS
• Study Type: interventional
• Target: 26
• Locations: 1 country
• Sites: 2

Brief Summary

Medical doctor generally are exposed to several risks and pressures, it is not a case that several meta-analyses have shown high stress and anxiety level in these workers. Stress management represents a very important topic. Being a doctor means dealing with continous effort and arousal management to provide the best treatment through executive functions capacity. This is particularly true for younger medical trainees; that have also to learn how to deal with failure and the curve of learning. Hypnosis has been shown to be very effective at modulating executive functions and sympathovagal balance, with large effect in post traumatic stress disease (PTSD), anxiety and executive function modulation. Therefore, this study aim to investigate if hypnosis could be beneficial among medical trainees for managing negative thoughts related to work.

Conditions

Stress; Stress Disorders

Keywords

stress; disorder; hypnosis

Outcome Measures

Primary Outcomes (2)

• Evaluation of the variations of the tonic and phasic component of the Electrodermal Activity (EDA,microSiemens) and Skin conductance response comparing pre and post-hypnosis (SCr/min)

  Evaluation of the variations of the tonic and phasic component of the Electrodermal Activity (EDA,microSiemens) and Skin conductance response comparing pre and post-hypnosis (SCr/min)

  T0) Within 3 minutes from electrodes application (at baseline), T1) within 3minute after a negative memory (w/o hypnosis), T2) within 3minutes after a positive memory, T3) within 3minutes after recalling the negative memory (after hypnosis application)

• Evaluation of the executive performance comparing pre- and post-hypnosis through Tower of London-Revised (TOL-R) (number of correct responses)

  Evaluation of the executive performance comparing pre- and post-hypnosis through Tower of London-Revised (TOL-R) (number of correct responses)

  Within 3 minutes from the first negative memory (without hypnosis) and then, within 3 minutes from the negative memory (with hypnosis)

Secondary Outcomes (2)

• Evaluation of the variations of psychological stress response to a negative memory related to work between pre and post hypnosis on a scale from 0 to 10

  Within 3 minutes from the first negative memory (without hypnosis) and then, within 3 minutes from the negative memory (with hypnosis)

• Evaluation of the Heart rate variability (HRV) comparing pre and post-hypnosis (ms)

  T0) Within 3 minutes from electrodes application (at baseline), T1) within 3minute after a negative memory (w/o hypnosis), T2) within 3minutes after a positive memory, T3) within 3minutes after recalling the negative memory (after hypnosis application)

Study Arms (2)

Hypnosis and negative memory (n. 26)

EXPERIMENTAL

T0) basal evaluation of physiological data T1) evaluation of physiological data after recollecting a negative memory for 3 minutes T2) evaluation of physiological data after that a brief session of hypnosis (performed with positive memories) T3) evaluation of physiological data recolling, for the second time, the negative memory.

Behavioral: Experimental: Hypnosis and negative memory

Control group (n. 23)

SHAM COMPARATOR

Active control group con breath-focused attention. Allocation: Non-randomized

Behavioral: Sham Comparator: Control group

Interventions

Experimental: Hypnosis and negative memory BEHAVIORAL

Arm Description: T0) basal evaluation of physiological data T1) evaluation of physiological data after recollecting a negative memory for 3 minutes T2) evaluation of physiological data after that a brief session of hypnosis (performed with positive memories) T3) evaluation of physiological data recolling, for the second time, the negative memory.

Hypnosis and negative memory (n. 26)

Sham Comparator: Control group BEHAVIORAL

Arm Description: Active control group con breath-focused attention. Allocation: Non-randomized

Control group (n. 23)

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• age \> 18 years old,
• being medical doctor or at first year of residency in Anesthesiology
• obtained written informed consent

You may not qualify if:

• Neurological issues affecting stress responses
• Diabetes
• Cardiovascular conditions (i.e., hypertension, orthostatic hypotension etc)
• Being under psychiatric medications
• Psychological or psychiatric diseases

Sponsors & Collaborators

• University of Padova: lead

Study Sites (2)

Istituto di Anestesia e Rianimazione

Padua, Italy, 35126, Italy

Location

University of Padova

Padua, PD, 35126, Italy

Location

Related Publications (1)

• Queirolo L, Boscolo A, Cracco T, Moscardi O, Facco E, Zanette G, Stellini E, Navalesi P. Hypnosis reshapes multilevel stress response and enhances executive performance in stressed medical students. Sci Rep. 2026 Feb 26;16(1):8844. doi: 10.1038/s41598-026-40770-6.

  PMID: 41748676 DERIVED

MeSH Terms

Conditions

Stress Disorders, Traumatic; Disease

Condition Hierarchy (Ancestors)

Trauma and Stressor Related Disorders; Mental Disorders; Pathologic Processes; Pathological Conditions, Signs and Symptoms

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NON RANDOMIZED
• Masking: NONE
• Purpose: SUPPORTIVE CARE
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Professor

Study Record Dates

• First Submitted: December 29, 2024
• First Posted: January 16, 2025
• Study Start: February 6, 2025
• Primary Completion: April 1, 2025
• Study Completion: April 1, 2025
• Last Updated: February 18, 2026

Record last verified: 2026-02

Data Sharing

• IPD Sharing: Will not share

Locations

IT (2)