The Impact of Lumboscopy Versus Laparoscopy on Ventilatory Mechanics

NCT06776068 | Not Yet Recruiting

• 1 other identifier: CR/23053
• Study Type: observational
• Target: 40
• Locations: 1 country
• Sites: 2

Brief Summary

There are several techniques for performing minimally invasive urological surgeries. Among them, laparoscopic surgery, robotic surgery, and lumboscopy are noteworthy (1). The medical literature extensively documents the impact of pneumoperitoneum a procedure involving the insufflation of the peritoneal cavity with carbon dioxide (CO2), which is essential for laparoscopic and robotic surgeries on ventilatory mechanics. As an alternative, CO2 insufflation into the retroperitoneum, as utilized in lumboscopic surgery, has been proposed. This approach is believed to exert a lesser impact on respiratory function and pulmonary mechanics. However, it is important to note that no conclusive evidence has yet been found to support this claim. Assessing the impact of lumboscopic surgery could help establish it as a viable alternative for patients with pulmonary conditions, where mechanical ventilation poses significant challenges. To explore this possibility, a physiological study was designed to compare the effects of laparoscopic and lumboscopic surgery on ventilatory mechanics.

Conditions

Anesthesia; Mechanical Ventilation; Respiratory Physiology

Keywords

Anesthesia; Lumboscopy; Mechanical Ventilation; Laparoscopy

Outcome Measures

Primary Outcomes (1)

• Parameters of ventilatory mechanics

  Static compliance Plateau pressure Driving pressure Transpulmonary pressure

  intraoperative

Study Arms (1)

Adult patients undergoing general anesthesia for laparoscopic and lumboscopic nephrectomy

Adult patients undergoing general anesthesia for laparoscopic and lumboscopic nephrectomy.

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Adult patients undergoing general anesthesia for minimally invasive nephrectomy

You may qualify if:

• Age \>18 years old
• ASA PS II-III
• Elective surgery
• Surgery: Partial or total nephrectomy

You may not qualify if:

• Severe pulmonary pathology
• Severe cardiovascular pathology
• Open surgery

Sponsors & Collaborators

• University of Chile: lead

Study Sites (2)

Hospital Clínico Universidad de CHile

Santiago, Chile

Location

Instituto Nacional del Cáncer

Santiago, Chile

Location

Related Publications (1)

• Guillonneau B, Ballanger P, Lugagne PM, Valla JS, Vallancien G. Laparoscopic versus lumboscopic nephrectomy. Eur Urol. 1996;29(3):288-91. doi: 10.1159/000473762.

  PMID: 8740033 BACKGROUND

Central Study Contacts

Roberto González, MD

CONTACT

+56999397515; robgonzalez@uchile.cl

Felipe Maldonado, MD

CONTACT

+56992160831; felitech@gmail.com

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Anesthesiologist

Study Record Dates

• First Submitted: January 9, 2025
• First Posted: January 15, 2025
• Study Start: February 1, 2025
• Primary Completion: March 1, 2025
• Study Completion: March 30, 2026
• Last Updated: January 15, 2025

Record last verified: 2024-12

Data Sharing

• IPD Sharing: Will not share

Locations

CL (2)