Scores in Critically Ill Patients After Craniotomy

NCT06762184 | Recruiting DMC

• 1 other identifier: JZhou-2
• Study Type: observational
• Target: 1,600
• Locations: 1 country
• Sites: 1

Brief Summary

This study planned to review patients admitted to three ICU wards at Beijing Tiantan Hospital between 2017 and 2020. It focused on adult patients who had undergone craniotomy and stayed in the ICU for more than 24 hours. Researchers intended to collect patient information, surgery details, complications, and outcomes from medical records. They also planned to gather routine scoring data used at the hospital and double-check its accuracy. Patients would be divided into two groups based on whether they survived or not, and the ability of different scoring systems to predict outcomes would be analyzed. Additionally, the study aimed to group patients by the type of surgery and assess how well the scoring systems predicted outcomes for each group.

Conditions

Post-craniotomy; Critical Illness; Mortality; Severity of Illness Scores

Keywords

critical ill; post-craniotomy; APACHE II; SOFA; SAPS II; GCS; GCS-P; mortality

Outcome Measures

Primary Outcomes (1)

• predictive value of different scoring systems

  We would evaluate the predictive value of different scoring systems for in-hospital mortality in critically ill patients following craniotomy.

  3 months

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Patients admitted to the ICU wards between 2017 and 2020 would be screened, and those who underwent craniotomy and had an ICU stay of more than 24 hours were eligible for inclusion. For patients with multiple ICU admissions during a single hospitalization, only the first admission was included. Pregnant or lactating women, as well as patients enrolled in other clinical studies, would be excluded.

You may qualify if:

• Patients admitted to the ICU wards between 2017 and 2020
• Patients underwent craniotomy
• Patientshad an ICU stay of more than 24 hours

You may not qualify if:

• Pregnant or lactating women
• Patients enrolled in other clinical studies

Sponsors & Collaborators

• Beijing Tiantan Hospital: lead

Study Sites (1)

Beijing Tiantan Hospital, Capital Medical University

Beijing, Beijing, 100070, Chile

RECRUITING

Related Publications (1)

• Zhou J, Luo XY, Li HL, Shi GZ, Chen GQ. Comparison of the predictive value of APACHE II, SOFA, SAPS II, GCS and GCS-P scores for in-hospital mortality in critically ill patients after craniotomy: a retrospective cohort study in a Chinese tertiary hospital. BMJ Open. 2026 Feb 4;16(2):e101867. doi: 10.1136/bmjopen-2025-101867.

  PMID: 41638721 DERIVED

MeSH Terms

Conditions

Critical Illness

Condition Hierarchy (Ancestors)

Disease Attributes; Pathologic Processes; Pathological Conditions, Signs and Symptoms

Central Study Contacts

Jianfang Zhou Zhou, MD

CONTACT

8610-59978451; zjfyanger@sina.com

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: January 1, 2025
• First Posted: January 7, 2025
• Study Start: November 1, 2024
• Primary Completion: March 1, 2025
• Study Completion: March 1, 2025
• Last Updated: February 11, 2025

Record last verified: 2025-01

Data Sharing

• IPD Sharing: Will share

Locations

CL (1)