Outcomes of Different Surgical Procedures After High Level Resection for Patients With Small Intestinal Gangrene

NCT06759727 | Not Yet Recruiting

• 1 other identifier: small bowel gangrene surgery
• Study Type: observational
• Target: 40
• Locations: 0 countries
• Sites: N/A

Brief Summary

In this cohort study, aim to evaluate and compare short-term postoperative outcomes of different surgical procedures for patients with intestinal gangrene who underwent high level small bowel resection (\< 150 cm from DJ).

Conditions

Small Bowel Gangrene; Mesenteric Artery Ischemia; Strangulated Hernia

Outcome Measures

Primary Outcomes (1)

• morality rate

  within 90 days of surgery

Study Arms (4)

Group A: Primary anastomosis: using hand sewing technique

Group B: Primary anastomosis with prophylactic tube enterostomy. Feeding jejunostomy may be inserted

Group C: Jejunostomy: double barrel stoma.

Group D: Jejunostomy: double barrel stoma with distal refeeding via the mucous fistula opening.

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

This study is a prospective non-randomized comparative study. Patients who will undergo high level small bowel resection for intestinal gangrene during the period from September 2024 to September 2026 are included.

You may qualify if:

• \) Distance of proximal resection margin less than 150 cm from DJ. 2) Mesenteric vascular ischemia. 3) Strangulating obstruction e.g. due to hernia, volvulus, band, etc.

You may not qualify if:

• \) Patients less than 18 years. 2) Patients with malignant disease. 3) Patients with almost all small bowel loops resected (\< 60 cm remaining).

Sponsors & Collaborators

• Assiut University: lead

Biospecimen

Retention: SAMPLES WITHOUT DNA

parts of small intestine

Central Study Contacts

mohamed mohamed Abdelsayed, garduate

CONTACT

+201095421323; mo7amad.moha1001@gmail.com

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Target Duration: 3 Years
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: resident

Study Record Dates

• First Submitted: December 29, 2024
• First Posted: January 6, 2025
• Study Start: January 1, 2025
• Primary Completion (Estimated): September 1, 2026
• Study Completion (Estimated): October 1, 2026
• Last Updated: January 7, 2025

Record last verified: 2025-01