NCT06754280

Brief Summary

RESET-CKD is evaluating an intervention to support Black adults with chronic kidney disease (CKD) to reduce their sedentary (e.g., sitting) time. Half of the participants will be randomized to the intervention, where the goal is to support individuals to reduce their sitting time, and the other half will be randomized to an attention control condition that provides CKD-related education not related to sedentary behavior. All participants will be followed for 12 weeks.

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
40

participants targeted

Target at P25-P50 for not_applicable

Timeline
11mo left

Started Mar 2025

Typical duration for not_applicable

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Progress59%
Mar 2025May 2027

First Submitted

Initial submission to the registry

December 23, 2024

Completed
8 days until next milestone

First Posted

Study publicly available on registry

December 31, 2024

Completed
2 months until next milestone

Study Start

First participant enrolled

March 13, 2025

Completed
1.5 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

September 1, 2026

Expected
8 months until next milestone

Study Completion

Last participant's last visit for all outcomes

May 1, 2027

Last Updated

February 23, 2026

Status Verified

July 1, 2025

Enrollment Period

1.5 years

First QC Date

December 23, 2024

Last Update Submit

February 19, 2026

Conditions

Chronic Kidney Disease(CKD)

Keywords

Sedentary

Outcome Measures

Primary Outcomes (1)

  • Change in sedentary time

    Change in activPAL-measured sedentary time

    Baseline to week 12

Secondary Outcomes (2)

  • Change in self-reported sedentary time

    Baseline to week 12

  • Change in health-related quality of life

    Baseline to week 12

Study Arms (2)

RESET-CKD

EXPERIMENTAL

RESET-CKD is a 12-week intervention that consists of four major components to support decreasing sedentary behavior: (1) health coaching, (2) feedback charts on sedentary behavior, (3) a workbook, and (4) reminders and cues.

Behavioral: RESET-CKD

Attention Control

ACTIVE COMPARATOR

CKD-related education

Other: Attention Control

Interventions

RESET-CKDBEHAVIORAL

RESET-CKD is a 12-week intervention that consists of four major components to support decreasing sedentary behavior: (1) health coaching, (2) feedback charts on sedentary behavior, (3) a workbook, and (4) reminders and cues.

RESET-CKD
Attention ControlOTHER

CKD-related education

Attention Control

Eligibility Criteria

Age35 Years - 80 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Self-identifies as Black or African American
  • Age ≥35 to ≤80 years old
  • CKD Stage 1-4
  • Self-reported 6 or more hours/day of sedentary time
  • Ability to speak/read/understand English
  • Has access to a telephone

You may not qualify if:

  • Being unable to walk 1 block
  • Being unable to stand from a seated position without assistance
  • Using a wheelchair, walker, or cane for all of their ambulation
  • Presence of a condition(s) or diagnosis, either physical or psychological, that precludes participation, including: Lower-extremity amputation (AKA or BKA) without prosthetic, Orthopedic condition that would preclude prompted sit-to-stand transitions or standing, Neurologic or psychiatric condition that would preclude prompted sit-to- stand transitions or standing, Severe cognitive impairment, Unstable coronary artery disease (i.e., angina with activity), Orthostatic hypotension
  • Kidney transplant
  • Any other condition that the investigator considers precludes participation in the trial
  • Participated in the Patient Advisory Board

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

UI Health/University of Illinois Chicago

Chicago, Illinois, 60612, United States

RECRUITING

MeSH Terms

Conditions

Renal Insufficiency, ChronicSedentary Behavior

Condition Hierarchy (Ancestors)

Renal InsufficiencyKidney DiseasesUrologic DiseasesFemale Urogenital DiseasesFemale Urogenital Diseases and Pregnancy ComplicationsUrogenital DiseasesMale Urogenital DiseasesChronic DiseaseDisease AttributesPathologic ProcessesPathological Conditions, Signs and SymptomsBehavior

Central Study Contacts

Mary Hannan, PhD

CONTACT

3123554838mhanna22@uic.edu

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
OTHER
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Assistant Professor

Study Record Dates

First Submitted

December 23, 2024

First Posted

December 31, 2024

Study Start

March 13, 2025

Primary Completion (Estimated)

September 1, 2026

Study Completion (Estimated)

May 1, 2027

Last Updated

February 23, 2026

Record last verified: 2025-07

Locations

US(1)