Outcomes of Isolated LCx Occlusion

NCT06750328 | Not Yet Recruiting DMC

• 1 other identifier: LCx occlusion
• Study Type: observational
• Target: 50
• Locations: 0 countries
• Sites: N/A

Brief Summary

To assess procedural success and short term clinical outcomes of primary PCI to isolated LCx acute occlusion.

Conditions

LCx Occlusion STEMI; STEMI

Keywords

LCx occlusion STEMI

Outcome Measures

Primary Outcomes (1)

• Complications of PPCI to LCx occlusion

  defined as angiographic success without in-hospital complications). Angiographic success (defined as in-stent residual stenosis ≤30% without serious angiographic complications (severe coronary dissection impairing flow \[type D-F\], perforation, abrupt closure or no reflow) .

  6 months

Secondary Outcomes (1)

• Long follow up of outcomes of PPCI of LCx outcomes

  6 months

Study Arms (1)

Follow up after PPCI

To assess procedural success and short term clinical outcomes of primary PCI to isolated LCx acute

Eligibility Criteria

• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

Baseline demographic, angiographic and clinical data, including cardiovascular risk factors, will be retrospectively collected. For follow up, we will contact every patient included in our study to ask about MACE.

You may qualify if:

• Patients presented to Assiut University heart hospital with STEMI who underwent primary PCI that revealed isolated LCx acute occlusion (single culprit artery) between January 2018 to January 2025 will be included.

You may not qualify if:

• Patients with cardiogenic shock, NYHA class III-IV and multivessel coronary artery disease will be excluded.

Sponsors & Collaborators

• Assiut University: lead

Related Publications (3)

• Geffin R, Triska J, Najjar S, Berman J, Cruse M, Birnbaum Y. Why do we keep missing left circumflex artery myocardial infarctions? J Electrocardiol. 2024 Mar-Apr;83:4-11. doi: 10.1016/j.jelectrocard.2023.12.011. Epub 2023 Dec 26.

  PMID: 38181483 BACKGROUND

• From AM, Best PJ, Lennon RJ, Rihal CS, Prasad A. Acute myocardial infarction due to left circumflex artery occlusion and significance of ST-segment elevation. Am J Cardiol. 2010 Oct 15;106(8):1081-5. doi: 10.1016/j.amjcard.2010.06.016.

  PMID: 20920642 BACKGROUND

• Stribling WK, Kontos MC, Abbate A, Cooke R, Vetrovec GW, Dai D, Honeycutt E, Wang TY, Lotun K. Left circumflex occlusion in acute myocardial infarction (from the National Cardiovascular Data Registry). Am J Cardiol. 2011 Oct 1;108(7):959-63. doi: 10.1016/j.amjcard.2011.05.027. Epub 2011 Aug 4.

  PMID: 21820644 BACKGROUND

MeSH Terms

Conditions

ST Elevation Myocardial Infarction

Condition Hierarchy (Ancestors)

Myocardial Infarction; Myocardial Ischemia; Heart Diseases; Cardiovascular Diseases; Vascular Diseases; Infarction; Ischemia; Pathologic Processes; Pathological Conditions, Signs and Symptoms; Necrosis

Central Study Contacts

Esraa Gamal Mohammed, Master student

CONTACT

+2 01158863129; alaajamal851@gmail.com

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Resident doctor

Study Record Dates

• First Submitted: December 16, 2024
• First Posted: December 27, 2024
• Study Start: December 16, 2024
• Primary Completion: December 12, 2025
• Study Completion (Estimated): November 12, 2027
• Last Updated: December 27, 2024

Record last verified: 2024-12

Data Sharing

• IPD Sharing: Will not share