NCT06748560

Brief Summary

Hamstring strains are among the most common injuries in field sports, accounting for 10% of all team sports injuries and often leading to long-term absence from activities. Risk factors include older age, previous injuries, reduced flexibility, and strength deficits. The hamstrings play a critical role in dynamic stability and joint preservation, particularly for the hip and knee. While stretching is crucial for injury prevention, there is debate over optimal techniques. The neurodynamic sliding technique (NST) and eccentric training (ET) are two methods that can improve flexibility and reduce injury risk. This study uniquely combines ET with NST to address hamstring tightness in athletes, aiming to evaluate their effects individually and in combination on knee muscle strength, range of motion, proprioception, and lower limb function compared to a control group. The hypotheses examine whether these interventions differ in their impact on eccentric and concentric knee strength, the knee flexor/extensor strength ratio, range of motion, proprioception, and dynamic balance (measured via the Y Balance Test). The null hypothesis (H0) proposes no differences, while the alternative hypothesis (H1) suggests significant differences among the intervention methods.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
54

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Aug 2023

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

August 4, 2023

Completed
4 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2023

Completed
10 months until next milestone

Study Completion

Last participant's last visit for all outcomes

October 1, 2024

Completed
2 months until next milestone

First Submitted

Initial submission to the registry

December 3, 2024

Completed
24 days until next milestone

First Posted

Study publicly available on registry

December 27, 2024

Completed
Last Updated

December 27, 2024

Status Verified

December 1, 2024

Enrollment Period

4 months

First QC Date

December 3, 2024

Last Update Submit

December 22, 2024

Conditions

Keywords

HamstringTightnessNeurodynamicsEccentric exercise

Outcome Measures

Primary Outcomes (1)

  • Passive Straight Leg Raise (SLR) test

    To measure passive hamstring flexibility, participants will lie supine on a bed with their pelvis and opposite thigh secured using straps to prevent compensatory movements. A goniometer will be positioned with its axis at the greater trochanter of the femur, the fixed arm aligned with the midaxillary line, and the moving arm along the lateral malleolus. With the knee extended and the ankle in a neutral position to avoid calf muscle stiffness, the thigh is gently flexed until hamstring tightness is felt. The straight leg's elevation angle will be measured three times, and the average will determine hamstring flexibility. Individuals with an angle less than 75° are classified as having short hamstring muscles.

    1-2 minutes

Secondary Outcomes (3)

  • Knee muscle strength

    10 minutes

  • Knee joint proprioception

    10 minutes

  • Y balance test

    15 minutes

Study Arms (4)

Eccentric training

ACTIVE COMPARATOR

The group is consist of 13 participants who did the following treatment protocol: The Nordic exercise served as the foundation for the intervention, focusing on eccentric loading as participants resisted falling forward. To minimize DOMS and ensure adherence, a two-week preparatory phase of mixed concentric/eccentric leg curls using a stability ball was implemented. Following this, the gradual progression outlined by Mjolsnes et al. led to a four-week Nordic hamstring curl regimen. Weekly supervision ensured proper technique and compliance throughout the program.

Other: Eccentric training

Neurodynamic sliding technique

ACTIVE COMPARATOR

The group is consist of 14 participants who did the following treatment protocol: The neurodynamic sliding technique (NST) was applied to the dominant leg's sciatic nerve in the NST and ETNST groups. The technique involves alternating stress proximally and distally to promote nerve sliding. Participants performed two sets of movements-cervical flexion with knee and ankle flexion, and cervical extension with knee and ankle extension-repeated actively for 60 seconds, five times per session. Over six weeks, both groups underwent three supervised sessions per week led by an experienced researcher.

Other: Neurodynamics

Eccentric training and neurodynamic sliding technique

EXPERIMENTAL

The group consist of 13 participants who did the following treatment protocol: They underwent a combined treatment incorporating both eccentric training (ET) and the neurodynamic sliding technique (NST). Participants followed the graduated Nordic hamstring exercise protocol for eccentric strengthening, alongside the nerve-sliding movements targeting the sciatic nerve. This combined approach aimed to optimize muscle flexibility, strength, and neural mobility. The interventions were performed over six weeks, with three supervised sessions per week to ensure proper execution and adherence.

Other: NeurodynamicsOther: Eccentric training

Control

NO INTERVENTION

Interventions

Following Castellote-Caballero et al., the neurodynamic sliding technique (NST) was applied to the dominant leg's sciatic nerve in the NST and ETNST groups. The technique involves alternating stress proximally and distally to promote nerve sliding. Participants performed two sets of movements-cervical flexion with knee and ankle flexion, and cervical extension with knee and ankle extension-repeated actively for 60 seconds, five times per session. Over six weeks, both groups underwent three supervised sessions per week led by an experienced researcher.

Eccentric training and neurodynamic sliding techniqueNeurodynamic sliding technique

The Nordic exercise served as the foundation for the intervention, focusing on eccentric loading as participants resisted falling forward. To minimize DOMS and ensure adherence, a two-week preparatory phase of mixed concentric/eccentric leg curls using a stability ball was implemented. Following this, the gradual progression outlined by Mjolsnes et al. led to a four-week Nordic hamstring curl regimen. Weekly supervision ensured proper technique and compliance throughout the program.

Eccentric trainingEccentric training and neurodynamic sliding technique

Eligibility Criteria

Age18 Years - 30 Years
Sexmale
Healthy VolunteersNo
Age GroupsAdult (18-64)

You may qualify if:

  • Age between 18-30 years old
  • Have a normal body mass index (BMI)
  • Have hamstring tightness as indicated by the results of an SLR examination of less than 75o (39).
  • Have hamstring tightness as indicated Active Knee Extension Test (AKET) was used to evaluate hamstring shortness. Individuals with AKET angles less than 150 degrees were considered as samples (146).
  • Ability to perform exercises.
  • Don't having plates (implants) in the lower limbs.
  • Not having a history of fracture in the lower limb (with or without realignment process).
  • Not having history of surgery to repair joint capsules, ligaments, muscles, and nerves,
  • A history of or experiencing Hernia Nucleus Pulposus (HNP).

You may not qualify if:

  • Receiving physical therapy or other conventional therapy in the past 6 months.
  • Absence in one of the pre- or post-test sessions.
  • Absence of more than two sessions in practice sessions.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Yeditepe university

Istanbul, Ataşehir, Turkey (Türkiye)

Location

Study Officials

  • Elif Tuğçe ÇİL, Assistant Prof. Dr.

    Physiotherapy and Rehabilitation department, Yeditepe University, istanbul, Turkey

    STUDY DIRECTOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Assistant Prof. Dr.

Study Record Dates

First Submitted

December 3, 2024

First Posted

December 27, 2024

Study Start

August 4, 2023

Primary Completion

December 1, 2023

Study Completion

October 1, 2024

Last Updated

December 27, 2024

Record last verified: 2024-12

Locations