Dyadic Psychological Stress Among Lung Cancer Patient-caregiver Dyads

NCT06746948 | Completed

• 1 other identifier: Dyadic psychological stress
• Study Type: observational
• Target: 254
• Locations: 1 country
• Sites: 1

Brief Summary

A lung cancer diagnosis has a huge impact on the psychological well-being of both patients and family caregivers. However, the current psychological stress status among dyads remains unclear. The investigators aimed to determine the prevalence of anxiety and depression and identify the factors that influence patients with lung cancer and their caregivers. The investigators will conduct a cross-sectional study of 254 dyads of lung cancer patients and family caregivers from four tertiary hospitals in Hunan Province, China from January 2021 to June 2021. Besides, the investigators used several instruments to collect data on depression, anxiety, illness perception, mindfulness, self-compassion, and dyadic coping. The independent samples t-test, analysis of one-way variance, Spearman's correlation analysis, and multiple linear regression analysis were employed. The results will recommend oncology nurses promptly screen high-risk patient-caregiver dyads who may suffer from severe psychological stress and provide them with targeted psychosocial interventions.

Conditions

Lung Cancers; Lung Cancer Patients

Outcome Measures

Primary Outcomes (2)

• depression

  The investigators measured dyadic depressive symptoms using the Patient Health Questionnaire-9 (PHQ-9), which is a 9-item questionnaire. Scores range from 0 to 27, with higher scores indicating more severe depression. According to Kroenke et al.'s scoring of the PHQ-9, a score of 0-4 indicates no depression, 5-9 indicates mild depression, 10-14 indicates moderate depression, 15-19 indicates moderate severe depression, and 20-27 indicates severe depression. The prevalence of depression is equal to the number of cases with a PHQ-9 score of 5 or greater divided by the total number of cases. Cronbach's alpha coefficients in this study were 0.85 and the KMO test value was 0.719, which showed good reliability and validity.

  From enrollment through study completion, an average of 6 months

• anxiety

  The investigators assessed anxious symptoms using the Generalized Anxiety Disorder-7 scale (GAD-7), which is a 7-item questionnaire. Scores range from 0 to 21, with higher scores indicating more severe anxiety. According to Spitzer et al's evaluation of GAD-7 scale, a score of 0-4 indicates no anxiety, 5-9 indicates mild anxiety, 10-14 indicates moderate anxiety, and 15-21 indicates severe anxiety. The prevalence of anxiety was defined as the number of cases with a GAD-7 score of 5 or greater divided by the total number of cases. Cronbach's alpha coefficients in this study were 0.93, respectively and KMO test value was 0.927, which showed good reliability and validity.

  From enrollment through study completion, an average of 6 months

Secondary Outcomes (4)

• Illness Perception

  From enrollment through study completion, an average of 6 months

• mindfulness

  From enrollment through study completion, an average of 6 months

• self-compassion

  From enrollment through study completion, an average of 6 months

• dyadic coping

  From enrollment through study completion, an average of 6 months

Study Arms (1)

lung cancer caregiver-caregiver dyads

Other: dyadic psychological distress

Interventions

dyadic psychological distress OTHER

There is no intervention among the cross-sectional study.

lung cancer caregiver-caregiver dyads

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

hospitalized patients with lung cancer diagnosed by pathological section or cytology and a primary caregiver with a cumulative caregiving time of more than 33 hours; and a family member of the patient with lung cancer, such as spouse, children, parents, or other relatives.

You may qualify if:

• As for patients: aged≥18 years; hospitalized patients with lung cancer diagnosed by pathological section or cytology; and relatively stable condition, conscious, and able to express their willingness correctly.
• As for caregivers: aged ≥18 years; a primary caregiver with a cumulative caregiving time of more than 33 hours; and a family member of the patient with lung cancer, such as spouse, children, parents, or other relatives.

You may not qualify if:

• As for patients: people with a combination of other cancers or serious life-threatening diseases; the presence of audiological disorders or previous mental or cognitive disorders, such as anxiety disorder, or depression disorder; and receiving mental disorder treatments.
• As for caregivers: formal caregivers with employment relationships, such as nannies; the presence of audiological disorders or previous mental disorders or cognitive disorders, such as anxiety disorder, depression disorder; and receiving mental disorder treatments.

Sponsors & Collaborators

• Central South University: lead

Study Sites (1)

Xiangya School of Nursing

Changsha, 410013, China

Location

Related Publications (1)

• Li J, Li C, Zou J, Cheng FQ, Peng L, Deng LH, Wu PP, Gao SY, Xiong ZY, Zuo Y, Luo Y, Rao XH, Yuan B, Chen OY, Zhang JP. Prevalence and influencing factors of the dyadic psychological stress among patients with lung cancer and their family caregivers: a cross-sectional study. BMC Nurs. 2025 Jan 6;24(1):13. doi: 10.1186/s12912-024-02635-z.

  PMID: 39762831 DERIVED

MeSH Terms

Conditions

Lung Neoplasms

Condition Hierarchy (Ancestors)

Respiratory Tract Neoplasms; Thoracic Neoplasms; Neoplasms by Site; Neoplasms; Lung Diseases; Respiratory Tract Diseases

Study Design

• Study Type: observational
• Observational Model: FAMILY BASED
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: lecturer

Study Record Dates

• First Submitted: December 15, 2024
• First Posted: December 24, 2024
• Study Start: January 1, 2021
• Primary Completion: June 30, 2021
• Study Completion: December 31, 2021
• Last Updated: December 27, 2024

Record last verified: 2024-12

Locations

CN (1)