Thorax Trauma Severity Score in Chest Trauma: A Study in Iraq

NCT06744959 | Recruiting DMC

• 1 other identifier: UNCOMIRB20241212B
• Study Type: observational
• Target: 166
• Locations: 1 country
• Sites: 1

Brief Summary

This prospective observational study aims to evaluate the predictive utility of the Thorax Trauma Severity Score (TTSS) in determining morbidity and mortality in patients presenting with chest trauma at a tertiary hospital in Iraq. The primary objectives of the study are: To assess the accuracy of TTSS in predicting mortality and critical outcomes such as ICU admission and the need for advanced interventions. To evaluate the utility of TTSS in stratifying patients based on injury severity in a resource-constrained setting. To identify demographic and clinical factors influencing the predictive performance of TTSS. Participants will: Be assessed using the TTSS upon arrival at the emergency department to establish risk stratification. Provide demographic and clinical data, including age, gender, mechanism of injury, comorbidities, and length of hospital stay, for analyzing associations with clinical outcomes.

Conditions

Chest Trauma

Keywords

TTSS; Chest; Trauma

Outcome Measures

Primary Outcomes (1)

• Accuracy Assessment of Thorax trauma severity score (TTSS) in Predicting In-Hospital Mortality

  The total score ranges from 0 to 25, with higher scores indicating more severe injuries, a poorer prognosis, and an increased risk of in-hospital mortality.

  From admission to hospital discharge or death, up to 30 days

Secondary Outcomes (4)

• Accuracy Assessment of the Thorax Trauma Severity Score (TTSS) in Predicting the Need for ICU Admission

  From emergency department admission to ICU admission, hospital discharge, or in-hospital death (up to 30 days).

• Accuracy Assessment of the Thorax Trauma Severity Score (TTSS) in Predicting Early Hospital Discharge

  From hospital admission to discharge, within 72 hours (early discharge).

• Accuracy Assessment of the Thorax Trauma Severity Score (TTSS) in Predicting the Need for Surgical Intervention

  From emergency department admission to surgical intervention, hospital discharge, or in-hospital death (up to 30 days).

• Accuracy Assessment of the Thorax Trauma Severity Score (TTSS) in Predicting In-Hospital Morbidity

  From hospital admission to discharge or death, up to 30 days.

Eligibility Criteria

• Age: 16 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

The study population includes adult patients aged 16 years and older presenting with chest trauma, including both blunt and penetrating injuries, at the emergency department of a tertiary hospital in Iraq. Participants will be evaluated for injury severity using the Thorax Trauma Severity Score (TTSS), with demographic and clinical data collected to explore outcome predictors. This population represents a diverse cohort reflective of trauma patterns in a resource-limited setting.

You may qualify if:

• patients above 16 years of age.
• Patients presenting to the emergency department with thoracic trauma.
• Patients or their legal guardians must provide informed consent to participate in the study.

You may not qualify if:

• Patients with incomplete clinical data or those discharged before scoring can be performed.
• Pregnant patients (due to specific physiological considerations not accounted for by the scoring system).
• Patients who succumb to their injuries before scoring or baseline data collection.
• chronic respiratory diseases
• malignancy and end-organ failure
• Patients with severe head injury (having extradural, subdural, subarachnoid, or intraparenchymal hemorrhage and skull bone fracture) or those requiring prior neurosurgical intervention
• patients with severe abdominal injury requiring surgical intervention like laparotomy

Sponsors & Collaborators

• Al-Nahrain University: lead

Study Sites (1)

College of Medicine - Al-Nahrain University

Baghdad, Iraq

RECRUITING

Related Publications (10)

• Moore EE, Malangoni MA, Cogbill TH, Shackford SR, Champion HR, Jurkovich GJ, McAninch JW, Trafton PG. Organ injury scaling. IV: Thoracic vascular, lung, cardiac, and diaphragm. J Trauma. 1994 Mar;36(3):299-300. No abstract available.

  PMID: 8145307 BACKGROUND

• Rating the severity of tissue damage. I. The abbreviated scale. JAMA. 1971 Jan 11;215(2):277-80. doi: 10.1001/jama.1971.03180150059012. No abstract available.

  PMID: 5107365 BACKGROUND

• Boyd CR, Tolson MA, Copes WS. Evaluating trauma care: the TRISS method. Trauma Score and the Injury Severity Score. J Trauma. 1987 Apr;27(4):370-8.

  PMID: 3106646 BACKGROUND

• Bozorgi F, Mirabi A, Chabra A, Mirabi R, Hosseininejad S-M, Zaheri H. Mechanisms of traumatic injuries in multiple trauma Patients. Int J Med Invest. 2018;7:7-15

  BACKGROUND

• Khandhar SJ, Johnson SB, Calhoon JH. Overview of thoracic trauma in the United States. Thorac Surg Clin. 2007 Feb;17(1):1-9. doi: 10.1016/j.thorsurg.2007.02.004.

  PMID: 17650692 BACKGROUND

• Aukema TS, Beenen LF, Hietbrink F, Leenen LP. Validation of the Thorax Trauma Severity Score for mortality and its value for the development of acute respiratory distress syndrome. Open Access Emerg Med. 2011 Aug 23;3:49-53. doi: 10.2147/OAEM.S22802. eCollection 2011.

  PMID: 27147852 RESULT

• Pape HC, Remmers D, Rice J, Ebisch M, Krettek C, Tscherne H. Appraisal of early evaluation of blunt chest trauma: development of a standardized scoring system for initial clinical decision making. J Trauma. 2000 Sep;49(3):496-504. doi: 10.1097/00005373-200009000-00018.

  PMID: 11003329 RESULT

• Wutzler S, Wafaisade A, Maegele M, Laurer H, Geiger EV, Walcher F, Barker J, Lefering R, Marzi I; Trauma Registry of DGU. Lung Organ Failure Score (LOFS): probability of severe pulmonary organ failure after multiple injuries including chest trauma. Injury. 2012 Sep;43(9):1507-12. doi: 10.1016/j.injury.2010.12.029. Epub 2011 Jan 21.

  PMID: 21256489 RESULT

• Clark GC, Schecter WP, Trunkey DD. Variables affecting outcome in blunt chest trauma: flail chest vs. pulmonary contusion. J Trauma. 1988 Mar;28(3):298-304. doi: 10.1097/00005373-198803000-00004.

  PMID: 3351988 RESULT

• Chrysou K, Halat G, Hoksch B, Schmid RA, Kocher GJ. Lessons from a large trauma center: impact of blunt chest trauma in polytrauma patients-still a relevant problem? Scand J Trauma Resusc Emerg Med. 2017 Apr 20;25(1):42. doi: 10.1186/s13049-017-0384-y.

  PMID: 28427480 RESULT

MeSH Terms

Conditions

Thoracic Injuries; Wounds and Injuries

Study Officials

• Luma K Mohammed, Assistant professor

  Al-Nahrain University

  STUDY DIRECTOR

Central Study Contacts

Abdulillah R. Khamees Al-Mamoori, MBBCH

CONTACT

07838571013; allaabed987@ced.nahrainuniv.edu.iq

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator

Study Record Dates

• First Submitted: December 12, 2024
• First Posted: December 20, 2024
• Study Start: July 22, 2025
• Primary Completion: May 1, 2026
• Study Completion (Estimated): May 10, 2026
• Last Updated: August 7, 2025

Record last verified: 2025-08

Data Sharing

• IPD Sharing: Will not share

Locations

IR (1)