Thorax vs. Trauma Injury Severity Scores as Outcome Predictors in Chest Trauma

NCT06707441 | Recruiting DMC

• 1 other identifier: UNCOMIRB20241125
• Study Type: observational
• Target: 150
• Locations: 1 country
• Sites: 1

Brief Summary

The goal of this observational study is to compare the predictive utility of the Thorax Trauma Severity Score (TTSS) and the Trauma and Injury Severity Score (TRISS) in determining outcomes among patients presenting with chest trauma to the emergency room. The main questions it aims to answer are: Does the TTSS provide a more accurate prediction of patient outcomes (e.g., mortality, ICU admission) than the TRISS? Are there specific patient subgroups where one score is more effective than the other? Participants will: Have their chest trauma severity assessed using both TTSS and TRISS during their emergency room admission. Have their clinical outcomes (e.g., mortality, ICU admission, length of hospital stay) monitored throughout their hospital stay.

Conditions

Chest Trauma

Keywords

TTSS; ER; TRISS

Outcome Measures

Primary Outcomes (3)

• In hospital mortality

  Mortality (death) during hospitalization.

  In-Hospital Phase (average of 7-10 days through discharge)

• Accuracy Assessment of Thorax Trauma Severity Score (TTSS)

  Range: from 0 to 25, with higher scores indicating more severe thoracic trauma.

  the first 6 hours after ER admission

• Accuracy Assessment of Trauma and Injury Severity Score (TRISS)

  Range: 0 (represents a 0% probability of survival) to 1 (represents a 100% probability of survival), with higher scores indicating greater trauma severity.

  the first 6 hours after ER admission

Secondary Outcomes (2)

• Length of Hospitalization

  Up to discharge, an average of 7-10 days

• Rate of admission to the intensive care unit (ICU)

  Up to discharge, an average of 7-10 days

Eligibility Criteria

• Age: 16 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

The study population will consist of adult patients (18 years and older) who present to the Emergency Department (ER) of Al-Kadhimiya Teaching Hospital with chest trauma. This population will be classified based on the severity of their injuries, ranging from minor to critical, and include both blunt and penetrating trauma cases.

You may qualify if:

• Patients with chest injuries that require clinical assessment using the Thorax Trauma Severity Score (TTSS) and the Trauma Injury Severity Score (TISS) within 6 hours of admission.
• Patients (or their legal guardians) must provide informed consent for participation in the study. This ensures ethical standards are maintained.
• Patients presenting with thoracic injuries, including rib fractures, pulmonary contusions, pneumothorax, hemothorax, and other chest-related injuries. This will include both isolated chest trauma and trauma with multiple injuries

You may not qualify if:

• Patients younger than 16 years.
• Patients with chest injuries caused by conditions unrelated to trauma, such as spontaneous pneumothorax, infections, or other medical conditions (e.g., non-traumatic rib fractures or cancer).
• Patients with severe co-morbidities (e.g., terminal illnesses, advanced stages of cancer, or end-stage organ failure) that would significantly affect outcomes unrelated to the chest trauma.
• Patients with pre-existing severe neurological conditions or other comorbidities that would interfere with trauma assessment and clinical management (e.g., severe brain injury, vegetative state).
• Patients or their legal representatives who refuse consent for participation in the study.
• Pregnant women due to potential risks associated with trauma and interventions during pregnancy.

Sponsors & Collaborators

• Al-Nahrain University: lead

Study Sites (1)

College of Medicine - Al-Nahrain University

Baghdad, Iraq

RECRUITING

Related Publications (13)

• Indurkar SK Sr, Ghormade PS, Akhade S, Sarma B. Use of the Trauma and Injury Severity Score (TRISS) as a Predictor of Patient Outcome in Cases of Trauma Presenting in the Trauma and Emergency Department of a Tertiary Care Institute. Cureus. 2023 Jun 14;15(6):e40410. doi: 10.7759/cureus.40410. eCollection 2023 Jun.

  PMID: 37456404 RESULT

• Zahran, M.R., Elwahab, A.A.E.M.A., El Nasr, M.M.A. et al. Evaluation of the predictive value of thorax trauma severity score (TTSS) in thoracic-traumatized patients. Cardiothorac Surg 28, 3 (2020). https://doi.org/10.1186/s43057-020-0015-7

  RESULT

• Imhoff BF, Thompson NJ, Hastings MA, Nazir N, Moncure M, Cannon CM. Rapid Emergency Medicine Score (REMS) in the trauma population: a retrospective study. BMJ Open. 2014 May 2;4(5):e004738. doi: 10.1136/bmjopen-2013-004738.

  PMID: 24793256 RESULT

• Karajizadeh M, Nasiri M, Yadollahi M, Zolfaghari AH, Pakdam A. Mortality Prediction from Hospital-Acquired Infections in Trauma Patients Using an Unbalanced Dataset. Healthc Inform Res. 2020 Oct;26(4):284-294. doi: 10.4258/hir.2020.26.4.284. Epub 2020 Oct 31.

  PMID: 33190462 RESULT

• Konesky KL, Guo WA. Revisiting traumatic cardiac arrest: should CPR be initiated? Eur J Trauma Emerg Surg. 2018 Dec;44(6):903-908. doi: 10.1007/s00068-017-0875-6. Epub 2017 Nov 25.

  PMID: 29177620 RESULT

• Mulvey HE, Haslam RD, Laytin AD, Diamond CA, Sims CA. Unplanned ICU Admission Is Associated With Worse Clinical Outcomes in Geriatric Trauma Patients. J Surg Res. 2020 Jan;245:13-21. doi: 10.1016/j.jss.2019.06.059. Epub 2019 Aug 5.

  PMID: 31394403 RESULT

• Todd KH, Lee T, Hoffman JR. The effect of ethnicity on physician estimates of pain severity in patients with isolated extremity trauma. JAMA. 1994 Mar 23-30;271(12):925-8.

  PMID: 8120961 RESULT

• Mondello S, Cantrell A, Italiano D, Fodale V, Mondello P, Ang D. Complications of trauma patients admitted to the ICU in level I academic trauma centers in the United States. Biomed Res Int. 2014;2014:473419. doi: 10.1155/2014/473419. Epub 2014 Jun 3.

  PMID: 24995300 RESULT

• Ramos-Pascua LR. Complications and trauma sequelae. Injury. 2018 Sep;49 Suppl 2:S1-S2. doi: 10.1016/j.injury.2018.06.045. Epub 2018 Jul 7. No abstract available.

  PMID: 30097308 RESULT

• Haagsma JA, Graetz N, Bolliger I, Naghavi M, Higashi H, Mullany EC, Abera SF, Abraham JP, Adofo K, Alsharif U, Ameh EA, Ammar W, Antonio CA, Barrero LH, Bekele T, Bose D, Brazinova A, Catala-Lopez F, Dandona L, Dandona R, Dargan PI, De Leo D, Degenhardt L, Derrett S, Dharmaratne SD, Driscoll TR, Duan L, Petrovich Ermakov S, Farzadfar F, Feigin VL, Franklin RC, Gabbe B, Gosselin RA, Hafezi-Nejad N, Hamadeh RR, Hijar M, Hu G, Jayaraman SP, Jiang G, Khader YS, Khan EA, Krishnaswami S, Kulkarni C, Lecky FE, Leung R, Lunevicius R, Lyons RA, Majdan M, Mason-Jones AJ, Matzopoulos R, Meaney PA, Mekonnen W, Miller TR, Mock CN, Norman RE, Orozco R, Polinder S, Pourmalek F, Rahimi-Movaghar V, Refaat A, Rojas-Rueda D, Roy N, Schwebel DC, Shaheen A, Shahraz S, Skirbekk V, Soreide K, Soshnikov S, Stein DJ, Sykes BL, Tabb KM, Temesgen AM, Tenkorang EY, Theadom AM, Tran BX, Vasankari TJ, Vavilala MS, Vlassov VV, Woldeyohannes SM, Yip P, Yonemoto N, Younis MZ, Yu C, Murray CJ, Vos T. The global burden of injury: incidence, mortality, disability-adjusted life years and time trends from the Global Burden of Disease study 2013. Inj Prev. 2016 Feb;22(1):3-18. doi: 10.1136/injuryprev-2015-041616. Epub 2015 Dec 3.

  PMID: 26635210 RESULT

• GBD 2021 Causes of Death Collaborators. Global burden of 288 causes of death and life expectancy decomposition in 204 countries and territories and 811 subnational locations, 1990-2021: a systematic analysis for the Global Burden of Disease Study 2021. Lancet. 2024 May 18;403(10440):2100-2132. doi: 10.1016/S0140-6736(24)00367-2. Epub 2024 Apr 3.

  PMID: 38582094 RESULT

• Lafta RK, Al-Nuaimi MA. National perspective on in-hospital emergency units in Iraq. Qatar Med J. 2013 Nov 1;2013(1):19-27. doi: 10.5339/qmj.2013.4. eCollection 2013.

  PMID: 25003053 RESULT

• Donaldson RI, Shanovich P, Shetty P, Clark E, Aziz S, Morton M, Hasoon T, Evans G. A survey of national physicians working in an active conflict zone: the challenges of emergency medical care in Iraq. Prehosp Disaster Med. 2012 Apr;27(2):153-61. doi: 10.1017/S1049023X12000519. Epub 2012 May 17.

  PMID: 22591705 RESULT

MeSH Terms

Conditions

Thoracic Injuries

Condition Hierarchy (Ancestors)

Wounds and Injuries

Study Officials

• Yaser aamer Eisa Alhaibi, Assistant professor

  College Of Medicine - Nahrain University

  STUDY DIRECTOR

Central Study Contacts

Abdulillah R. Khamees

CONTACT

+9647838571013; allaabed987@ced.nahrainuniv.edu.iq

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator

Study Record Dates

• First Submitted: November 24, 2024
• First Posted: November 27, 2024
• Study Start: January 20, 2025
• Primary Completion (Estimated): December 10, 2026
• Study Completion (Estimated): December 20, 2026
• Last Updated: March 4, 2026

Record last verified: 2026-03

Data Sharing

• IPD Sharing: Will not share

Locations

IR (1)