Role of MRI Breast in Detection of Ductal Carcinoma in Situ

NCT06744140 | Active Not Recruiting DMC

• 1 other identifier: MSAHS/Batch-Spring23/018
• Study Type: observational
• Target: 35
• Locations: 1 country
• Sites: 1

Brief Summary

"This study investigates the role of Magnetic Resonance Imaging (MRI) in detecting Ductal Carcinoma in situ (DCIS) in high-risk breast cancer patients.

Conditions

Carcinoma in Situ

Outcome Measures

Primary Outcomes (2)

• sensitivity & specificity

  sensitivity \& specificity of MRI in detecting DCIS

  12 Months

• BIRADS scores

  BIRADS scores will be used to evaluate the diagnostic accuracy of MRI in detecting DCIS

  12 Months

Interventions

Magnetic Resonance Imaging (MRI) DIAGNOSTIC_TEST

To Evaluate the breast Magnetic Resonance Imaging (MRI) in detecting Ductal Carcinoma In Situ (DCIS) lesions among high-risk breast cancer patients while keeping the histopathology as a GOLD standard

Eligibility Criteria

• Age: 30 Years - 65 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

To Evaluate the breast Magnetic Resonance Imaging (MRI) in detecting Ductal Carcinoma In Situ (DCIS) lesions among high-risk breast cancer patients while keeping the histopathology as a GOLD standard

You may qualify if:

• High-risk breast cancer patients with a family history of breast cancer or genetic predispositions (e.g., BRCA mutations).
• Patients aged 30-65 years.
• Patients willing to undergo breast MRI screening for DCIS detection.

You may not qualify if:

• Patients with contraindications to MRI imaging (e.g., pacemakers, claustrophobia).
• Patients with a history of prior breast surgery or interventions that may interfere with imaging interpretation.

Sponsors & Collaborators

• Superior University: lead

Study Sites (1)

INMOL hospital

Lahore, Punjab Province, Pakistan

Location

MeSH Terms

Conditions

Carcinoma in Situ

Interventions

Magnetic Resonance Imaging

Condition Hierarchy (Ancestors)

Carcinoma; Neoplasms, Glandular and Epithelial; Neoplasms by Histologic Type; Neoplasms

Intervention Hierarchy (Ancestors)

Tomography; Diagnostic Imaging; Diagnostic Techniques and Procedures; Diagnosis

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator

Study Record Dates

• First Submitted: December 17, 2024
• First Posted: December 20, 2024
• Study Start: February 15, 2024
• Primary Completion: July 1, 2024
• Study Completion: March 21, 2025
• Last Updated: December 20, 2024

Record last verified: 2024-12

Data Sharing

• IPD Sharing: Will not share

Locations

PA (1)