Comprehensive Demographics and Clinical Profile of NSCLC Patients

NCT06725537 | Not Yet Recruiting

• 1 other identifier: CA209-1529
• Study Type: observational
• Target: 500
• Locations: 0 countries
• Sites: N/A

Brief Summary

Advances in the treatment of non-small cell lung cancer in the last decade have been significant. Currently, there are several first-line therapeutic options. The molecular biology of the disease, biomarkers and the patient's clinical characteristics can assist in decision making. The study in question aims to retrospectively evaluate the patterns of choice in the first line treatment of metastatic non-small cell lung cancer without driver mutations, from 2019 to 2022 in 7 centers in Brazil.

Conditions

Lung Cancer Non Small Cell

Keywords

neoplasia; lung; metastasis; first line treatment

Outcome Measures

Primary Outcomes (2)

• treatment regimen decision option one

  immunotherapy versus chemotherapy, this outcome will be evaluated based on data from medical records and available laboratory results

  In 30 days

• treatment regimen decision option two

  dual immunotherapy, this outcome will be evaluated based on data from medical records and available laboratory results

  In 30 days

Secondary Outcomes (1)

• Survival analysis

  In 24 months

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Patients with a histological diagnosis of advanced non-small cell lung cancer, over 18 years of age

You may qualify if:

• Over 18 years old;
• Histological diagnosis of advanced non-small cell cancer;
• Clinical and demographic data available in medical records;

You may not qualify if:

• Patients with localized disease that can be treated locally;
• Non-epithelial histology;
• small cell carcinoma
• neuroendocrine tumor

Sponsors & Collaborators

• D'Or Institute for Research and Education: lead
• Bristol-Myers Squibb: collaborator

MeSH Terms

Conditions

Carcinoma, Non-Small-Cell Lung; Neoplasms; Neoplasm Metastasis

Condition Hierarchy (Ancestors)

Carcinoma, Bronchogenic; Bronchial Neoplasms; Lung Neoplasms; Respiratory Tract Neoplasms; Thoracic Neoplasms; Neoplasms by Site; Lung Diseases; Respiratory Tract Diseases; Neoplastic Processes; Pathologic Processes; Pathological Conditions, Signs and Symptoms

Study Officials

• Sofia V Mendes, MD

  Instituto D'Or de Pesquisa e Ensino

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Sofia V Mendes, MD

CONTACT

+55 (21) 999165250; sofiavidaurre@hotmail.com

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: December 5, 2024
• First Posted: December 10, 2024
• Study Start: January 20, 2025
• Primary Completion: March 1, 2025
• Study Completion: August 1, 2025
• Last Updated: January 15, 2025

Record last verified: 2025-01

Data Sharing

• IPD Sharing: Will not share