Black and African Americans Connections to Parkinson's Disease (BLAAC PD)
BLAAC PD
1 other identifier
observational
2,000
1 country
12
Brief Summary
BLAAC PD is a research study to understand what Parkinson's disease looks like for Black and African American communities. BLAAC PD is happening at research centers around the United States. The study is part of the Global Parkinson's Genetics Program (GP2). GP2 is a research project working to transform understanding of the genetics of Parkinson's disease and make that knowledge globally relevant.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started Nov 2020
Longer than P75 for all trials
12 active sites
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
November 16, 2020
CompletedFirst Submitted
Initial submission to the registry
December 2, 2024
CompletedFirst Posted
Study publicly available on registry
December 6, 2024
CompletedPrimary Completion
Last participant's last visit for primary outcome
December 31, 2027
ExpectedStudy Completion
Last participant's last visit for all outcomes
December 31, 2027
February 27, 2026
February 1, 2026
7.1 years
December 2, 2024
February 25, 2026
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Explore novel risk factors and characterization
To explore novel risk factors and characterization of known genetic risk factors contributing to Parkinson's disease risk in the Black and African American population.
5 years
Study Arms (2)
Participants with Parkinson's Disease
Data collected from these participants include demographic information and family health history. Participants may also complete a physical exam. Participants also complete a smell test and contribute a blood or saliva sample for genetic analyses.
Control Participants
Data collected from these participants include demographic information and family health history. Participants also complete a smell test and contribute a blood or saliva sample for genetic analyses.
Eligibility Criteria
Black Americans and African Americans with Parkinson's Disease or without a history of Parkinson's (control volunteers).
You may qualify if:
- Ability to provide informed consent
- Age 50 years or older
- Self-identify as Black or African American
You may not qualify if:
- Diagnosis of Parkinson's Disease and/or neurological condition
- Familial history of PD and/or neurodegenerative or psychiatric conditions
- Unknown family history of PD and/or neurodegenerative or psychiatric conditions
- Any conditions that, in the investigator's opinion, preclude the individual's ability to carry out study activities
- If submitting a saliva sample, nothing by mouth (food, drink, gum, tobacco, or smoking) for 30 minutes prior to sample collection
- Ability to provide informed consent
- Age 18 years or older
- Self-identify as Black or African American
- Meet the Movement Disorder Society's clinical diagnostic criteria for Parkinson's disease
- \- If submitting a saliva sample, nothing by mouth (food, drink, gum, tobacco, or smoking) for 30 minutes prior to sample collection
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- Rush Universitycollaborator
- Washington University School of Medicinecollaborator
- University Hospitals Cleveland Medical Centercollaborator
- University of Floridacollaborator
- The University of Texas Health Science Center, Houstoncollaborator
- Ochsner Health Systemcollaborator
- Indiana Universitycollaborator
- Michael J. Fox Foundation for Parkinson's Researchlead
- University of Chicagocollaborator
- University of Alabama at Birminghamcollaborator
- Medical University of South Carolinacollaborator
- Louisiana State University Health Sciences Center Shreveportcollaborator
- University of Marylandcollaborator
Study Sites (12)
University of Alabama at Birmingham
Birmingham, Alabama, 35233, United States
University of Florida
Gainesville, Florida, 32608, United States
Rush University
Chicago, Illinois, 60612, United States
University of Chicago
Chicago, Illinois, 60637, United States
Ochsner Clinic Foundation
New Orleans, Louisiana, 70121, United States
Louisiana State University Health Sciences Center Shreveport
Shreveport, Louisiana, 71103, United States
University of Maryland
Baltimore, Maryland, 21201, United States
Kaiser Permanente Midatlantic States
Rockville, Maryland, 20852, United States
Washington University in St. Louis
St Louis, Missouri, 63119, United States
University Hospitals Cleveland Medical Center
Cleveland, Ohio, 44106, United States
Medical University of South Carolina
Charleston, South Carolina, 29425, United States
University of Texas Health Science Center, Houston
Houston, Texas, 77030, United States
Related Publications (1)
Chahine, L.M., Louie, N., Solle, J. et al. The Black and African American Connections to Parkinson's Disease (BLAAC PD) study protocol. BMC Neurol 24, 403 (2024). https://doi.org/10.1186/s12883-024-03914-7
BACKGROUND
Related Links
Biospecimen
Whole blood or saliva
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Lana Chahine, MD, PhD
University of Pittsburgh
Central Study Contacts
Study Design
- Study Type
- observational
- Observational Model
- CASE CONTROL
- Time Perspective
- CROSS SECTIONAL
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
December 2, 2024
First Posted
December 6, 2024
Study Start
November 16, 2020
Primary Completion (Estimated)
December 31, 2027
Study Completion (Estimated)
December 31, 2027
Last Updated
February 27, 2026
Record last verified: 2026-02