NCT06718699

Brief Summary

Resistance exercise training (RT) is a key component of health related exercise programs. However, an accurate specification of RT load prescription is essential for effective and safe achievement of training aims. Proper specification of exercise intensity might be the most critical issue when designing RT protocols for adults. One repetition maximum tests (1RM) have been considered the "gold standard" of dynamic maximum strength evaluation. Although the argument of increased risk of injuries and adverse effects with 1RM testing in older people has been rejected by several studies , limited motivation to lift maximum loads, requirement for high test effort, time constraints, and interruption of the continuity of the training process aggravate the frequent application of 1RM tests particularly in non-athletic RT. 1RM prediction equations that use the load and number of repetitions completed to fatigue (RTF) to predict repetition maximum might be a reliable and feasible option to 1RM testing. Thus, the primary aims of this study were to evaluate the predictive accuracy of current RTF equations and to develop an equation that more accurately predicts 1RM from RTF tests.

Trial Health

75
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
120

participants targeted

Target at P50-P75 for all trials

Timeline
5mo left

Started Dec 2024

Geographic Reach
1 country

1 active site

Status
enrolling by invitation

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress78%
Dec 2024Sep 2026

First Submitted

Initial submission to the registry

December 1, 2024

Completed
1 day until next milestone

Study Start

First participant enrolled

December 2, 2024

Completed
3 days until next milestone

First Posted

Study publicly available on registry

December 5, 2024

Completed
1.7 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 31, 2026

Expected
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

September 30, 2026

Last Updated

January 29, 2026

Status Verified

January 1, 2026

Enrollment Period

1.7 years

First QC Date

December 1, 2024

Last Update Submit

January 28, 2026

Conditions

Keywords

maximum strengthone repetition maximumrepetitions to fatigueprediction equationresistance exercise

Outcome Measures

Primary Outcomes (1)

  • Maximum load, one repetition maximum, leg press

    Maximum load lifted once (1RM, in kg) for the leg press exercise

    At baseline - no follow up tests

Secondary Outcomes (27)

  • Maximum load lifted at 5-8RM, leg press

    At baseline - no follow up tests

  • Maximum load lifted at 9-12RM, leg press

    At baseline - no follow up tests

  • Maximum load lifted at 13-16 RM, leg press

    At baseline - no follow up tests

  • Maximum load, one repetition maximum, lat pulls

    At baseline - no follow up tests

  • Maximum load lifted at 5-8 RM, lat pulls

    At baseline - no follow up tests

  • +22 more secondary outcomes

Interventions

One 1RM and three RTF tests (5-8RM, 9-12RM, 13-16RM) on seven resistance training devices

Eligibility Criteria

Age18 Years - 85 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

The study population consists of resistance trained and untrained women and men 18 to 35 or 60-85 years old that are able to complete 1RM and RTF tests without endangering their health

You may qualify if:

  • to 35 years old
  • to 85 years old

You may not qualify if:

  • Contraindication for one repetition maximum tests
  • musculoskeletal injuries that may prevent a reliable and safe assessment of the 1RM and RTF tests

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Institute of Radiology, University Hospital NErlangen

Erlangen, 91054, Germany

Location

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
CROSS SECTIONAL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Professor Dr. PhD, Research Director

Study Record Dates

First Submitted

December 1, 2024

First Posted

December 5, 2024

Study Start

December 2, 2024

Primary Completion (Estimated)

August 31, 2026

Study Completion (Estimated)

September 30, 2026

Last Updated

January 29, 2026

Record last verified: 2026-01

Locations