Cluster Resistance Training and Older Adults

NCT06588842 | Completed

• 1 other identifier: 20240776
• Study Type: interventional
• Target: 25
• Locations: 1 country
• Sites: 1

Brief Summary

This project will focus on improving power in older adults, since power is related to performance of daily activities and memory and decision making. The study will compare cluster set resistance training, where you can rest during a set, to traditional set resistance training where all repetitions in a set must be completed without any between-repetition rest. If cluster set resistance training is better than traditional set resistance training, it could be more beneficial than existing methods in improving independence in older persons.

Conditions

Healthy Aging

Keywords

Resistance Training

Outcome Measures

Primary Outcomes (2)

• Change in neuromuscular performance as measured by power production.

  This test measures the power a person can produce at maximal speed using a load of 50% of 1RM for the chest press and leg press. There are no minimum or maximum scores. The higher score is better. Power shows how fast a person can do work. The test typically takes about five minutes. Unit of measure is Watts.

  Baseline, 12 weeks

• Change in neuromuscular performance as measured by 1-repetition maximum (1RM)

  Maximal load that can be lifted in one repetition (1RM) will be assessed for in both leg press and chest press exercises. The loads on the testing equipment will be increased over 5 to 7 testing sets. The persons 1RM will be the highest load the person can move through the range of motion of the exercise. There are no minimum or maximum scores for this test. The test typically takes 5 to 10 minutes. The higher the 1RM the stronger the person is.

  Baseline, 12 weeks

Secondary Outcomes (14)

• Change in Montreal Cognitive Assessment (MoCA)

  Baseline, 12 weeks

• Change in the Hopkins Verbal Learning Test

  Baseline, 12 weeks

• Change in Concept Switching as measured by the Dimensional Card Sort test.

  Baseline, 12 weeks

• Change in the Flanker test

  Baseline, 12 weeks

• Change in Event Memory as measured by the Picture Sequence Memory Test

  Baseline, 12 weeks

Study Arms (2)

Cluster Set Resistance Training

EXPERIMENTAL

Participants in this group will receive high-speed resistance training 2 times a week for 12 consecutive weeks.

Other: Cluster Set Resistance Training

Traditional Set Resistance Training

ACTIVE COMPARATOR

Participants in this group will receive traditional set resistance training 2 times a week for 12 consecutive weeks.

Other: Traditional Set Resistance Training

Interventions

Cluster Set Resistance Training OTHER

Participants will receive a total of 24 in-person training sessions using three sets of eight repetitions per set. During training participants will be allowed 1-minute rests between sets and 15-second rests after repetitions three and six.

Cluster Set Resistance Training

Traditional Set Resistance Training OTHER

Participants will receive a total of 24 in-person training sessions using three sets of eight repetitions per set. During training participants will be allowed 1-minute rests between sets.

Traditional Set Resistance Training

Eligibility Criteria

• Age: 55 Years - 85 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Montreal Cognitive Assessment Score \> 23
• No memory complaints

You may not qualify if:

• Uncontrolled cardiovascular or neuromuscular disease that prevents participation in a training program
• Any systemic inflammatory or autoimmune conditions such as rheumatoid arthritis, system lupus erythematosus, or other serious concomitant medical illness
• Unresolved injury or surgery to the upper or lower limbs.

Sponsors & Collaborators

• University of Miami: lead

Study Sites (1)

Laboratory of Neruomuscular Research and Active Aging

Coral Gables, Florida, 33147, United States

Location

Study Officials

• Joseph F. Signorile, PhD

  University of Miami

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Professor

Study Record Dates

• First Submitted: August 1, 2024
• First Posted: September 19, 2024
• Study Start: October 1, 2024
• Primary Completion: February 20, 2025
• Study Completion: February 20, 2025
• Last Updated: March 3, 2025

Record last verified: 2025-02

Data Sharing

• IPD Sharing: Will not share

Locations

US (1)