The Value of Near-infrared Spectroscopy and Blood Pressure Measurements in Estimating Future Fall Risk in Older Adults

NCT06714565 | Recruiting DMC

• 1 other identifier: NL85457.018.24
• Study Type: observational
• Target: 141
• Locations: 1 country
• Sites: 1

Brief Summary

The investigators aim to study which measurements/definitions from continuous blood pressures measurements (using a Finometer) and from cerebral oxygenation measurements (using near-infrared spectroscopy (NIRS)) are associated with future fall incidents in older adults at risk of falls.

Conditions

Falls; Orthostatic Hypotension; Older Adults (65 Years and Older)

Keywords

falls; orthostatic hypotension; blood pressure; NIRS; Older adults

Outcome Measures

Primary Outcomes (1)

• Falls during follow-up

  Falls data prospectively collected using fall calenders.

  From enrollment to 12 months follow-up

Study Arms (1)

Older adults who have experienced a fall.

Eligibility Criteria

• Age: 65 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Adults aged 65 years and over referred to the outpatient (fall) clinic who have experienced a fall in the past 12 months.

You may qualify if:

• years or older
• History of a fall (in the past year)
• Ability to perform supine-to-stand manoeuvres.
• Ability to sign informed consent.
• a Mini-Mental State Examination (MMSE) score of 21 points or higher or a Montreal Cognitive Assessment (MOCA) - Dutch score of 16 points or higher.
• Sufficient command of the Dutch language

You may not qualify if:

• Physically not able to perform sit-to-stand and supine-to-stand manoeuvres.
• Estimated life expectancy of less than one year.

Sponsors & Collaborators

• Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA): lead

Study Sites (1)

Amsterdam University Medical Center, location Meibergdreef

Amsterdam, 1105AZ, Netherlands

RECRUITING

MeSH Terms

Conditions

Hypotension, Orthostatic

Condition Hierarchy (Ancestors)

Orthostatic Intolerance; Primary Dysautonomias; Autonomic Nervous System Diseases; Nervous System Diseases; Hypotension; Vascular Diseases; Cardiovascular Diseases

Central Study Contacts

Anouschka C. Pronk, MD, PhD student

CONTACT

+31205669111; a.c.pronk@amsterdamumc.nl

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Prof.

Study Record Dates

• First Submitted: November 28, 2024
• First Posted: December 3, 2024
• Study Start: December 4, 2024
• Primary Completion (Estimated): December 4, 2026
• Study Completion (Estimated): December 5, 2026
• Last Updated: December 19, 2024

Record last verified: 2024-12

Locations

NL (1)