NCT06712901

Brief Summary

NORC/AmeriSpeak will recruit participants who meet the study criteria and invite them to complete a 15-minute survey. Participants will be randomly assigned to one of five conditions, with approximately 400 people in each condition, and will respond to various questions after viewing the study messaging. Once 2,000 participants complete the survey, the data will be de-identified and provided to the study team for analysis.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
2,030

participants targeted

Target at P75+ for not_applicable colorectal-cancer

Timeline
Completed

Started Jan 2025

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

November 19, 2024

Completed
13 days until next milestone

First Posted

Study publicly available on registry

December 2, 2024

Completed
1 month until next milestone

Study Start

First participant enrolled

January 9, 2025

Completed
12 days until next milestone

Primary Completion

Last participant's last visit for primary outcome

January 21, 2025

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

January 21, 2025

Completed
1.2 years until next milestone

Results Posted

Study results publicly available

March 20, 2026

Completed
Last Updated

March 20, 2026

Status Verified

March 1, 2026

Enrollment Period

12 days

First QC Date

November 19, 2024

Results QC Date

January 16, 2026

Last Update Submit

March 18, 2026

Conditions

Outcome Measures

Primary Outcomes (2)

  • Intentions to Adhere to Colorectal Cancer Screening (CRCS) Recommendations

    After reading cancer screening (CRCS) recommendations, this outcome will assess how likely they are to follow on the the screening recommendations. Response options: Very unlikely (1), unlikely, neither unlikely nor likely, likely, very likely (5) A higher score indicates a favorable outcome, and a lower score indicates a less favorable outcome.

    15 minutes

  • Intentions to Adhere Test Preference Indication

    To determine which colorectal cancer screening (CRCS) participants are most likely to choose. Response options: stool-based tests (e.g., FOBT or FIT); endoscopic/scoping approach (e.g., colonoscopy or sigmoidoscopy); whatever my doctor recommends to me; something other than a stool-based or scoping approach; I would not follow the recommendations. This outcome will report the count of responses.

    15 minutes

Secondary Outcomes (2)

  • Likelihood of Sharing Information Via Social Media

    15 minutes

  • Information Sharing Behavior

    15 minutes

Study Arms (5)

Control (no exposure)

PLACEBO COMPARATOR

Participants in the Control Arm will not be shown any messages.

Behavioral: Control

Median Ranked

EXPERIMENTAL

Participants in the Median Ranked Arm will be shown four Median Ranked messages.

Behavioral: Median Ranked Cancer Screening Messaging

Overall Preferred

EXPERIMENTAL

Participants in the Overall Preferred arm will be shown four Overall Preferred messages.

Behavioral: Overall Preferred Cancer Screening Messaging

Black American Preferred

EXPERIMENTAL

Participants in the Black American Preferred arm will be shown four Black American Preferred messages.

Behavioral: Black American Preferred Cancer Screening Messaging

White American Preferred

EXPERIMENTAL

Participants in the White American Preferred arm will be shown four White American Preferred messages.

Behavioral: White American Preferred Cancer Screening Messaging

Interventions

Strong message content that increases screening and sharing intentions. Messages in this intervention were highly rated messages by Black participants but not White participants in the prior study.

Black American Preferred

Strong message content that increases screening and sharing intentions. Messages in this intervention were highly rated messages by White participants but not Black participants.

White American Preferred
ControlBEHAVIORAL

There will be no message content of cancer screening and sharing intentions in this arm.

Control (no exposure)

Strong message content that increases screening and sharing intentions. Messages in this intervention were median ranked in the prior study.

Median Ranked

Strong message content that increases screening and sharing intentions. Messages in this intervention were highly rated messages by all participants in the prior study.

Overall Preferred

Eligibility Criteria

Age45 Years - 75 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Identify as white/Caucasian or Black/African American.

You may not qualify if:

  • Do not identify as white/Caucasian or Black/African American.
  • Previously diagnosed with colorectal cancer
  • Non-English speakers

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Andy King

Salt Lake City, Utah, 84112, United States

Location

MeSH Terms

Conditions

Colorectal Neoplasms

Condition Hierarchy (Ancestors)

Intestinal NeoplasmsGastrointestinal NeoplasmsDigestive System NeoplasmsNeoplasms by SiteNeoplasmsDigestive System DiseasesGastrointestinal DiseasesColonic DiseasesIntestinal DiseasesRectal Diseases

Results Point of Contact

Title
Andy King
Organization
University of Utah

Study Officials

  • Andy King, PhD

    Huntsman Cancer Institute/ University of Utah

    PRINCIPAL INVESTIGATOR

Publication Agreements

PI is Sponsor Employee
Yes

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
PARTICIPANT
Purpose
PREVENTION
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

November 19, 2024

First Posted

December 2, 2024

Study Start

January 9, 2025

Primary Completion

January 21, 2025

Study Completion

January 21, 2025

Last Updated

March 20, 2026

Results First Posted

March 20, 2026

Record last verified: 2026-03

Data Sharing

IPD Sharing
Will share

De-identified data will be shared/uploaded to an online data repository like OSF.

Shared Documents
STUDY PROTOCOL, SAP, ICF, ANALYTIC CODE
Time Frame
Once the primary results are published in a peer-reviewed journal article, the de-identified data will be published in an online data repository. The data will then be available for as long as the online repository is available

Locations