TRISS as a Predictor of Trauma Patient Outcomes

NCT06711536 | Completed DMC

• 1 other identifier: UNCOMIRB20241134
• Study Type: observational
• Target: 204
• Locations: 1 country
• Sites: 1

Brief Summary

The goal of this prospective observational study is to evaluate the predictive utility of the Trauma and Injury Severity Score (TRISS) in determining patient outcomes, including survival and mortality, among trauma patients admitted to the trauma and emergency department of Kadhimiya Educational Hospital, Iraq. The main questions it aims to answer are: How accurately does TRISS predict survival and mortality outcomes in trauma patients? What is the performance of TRISS in predicting secondary outcomes, such as the need for intensive care, surgical interventions, and length of hospital stay? Participants will: Be assessed using the TRISS score upon their admission to the emergency department. Have their clinical outcomes, including survival, need for intensive care, surgery, and hospital stay, monitored throughout their hospitalization.

Conditions

Trauma, Multiple

Keywords

TRISS

Outcome Measures

Primary Outcomes (4)

• Accuracy Assessment of TRISS in Predicting In-Hospital Mortality

  This outcome evaluates the ability of the Trauma and Injury Severity Score (TRISS), which generates a probability of survival ranging from 0% to 100%, to predict in-hospital mortality among trauma patients. Lower TRISS survival probabilities are expected to correlate with increased observed mortality.

  From admission to hospital discharge or death, up to 30 days.

• Accuracy Assessment of TRISS in Predicting the Need for Intervention

  This outcome examines the predictive value of TRISS (range: 0-100% survival probability) in determining the likelihood of trauma patients requiring major interventions (such as surgical procedures, blood transfusion, or invasive monitoring). Lower TRISS survival probabilities are expected to correlate with increased intervention requirements.

  From admission to hospital discharge or death, up to 30 days.

• Accuracy Assessment of TRISS in Predicting the Need for Endotracheal Intubation

  This outcome assesses the predictive performance of TRISS (range: 0-100% survival probability) in identifying trauma patients requiring endotracheal intubation during hospitalization. Lower TRISS survival probabilities are expected to be associated with an increased likelihood of intubation.

  From emergency department admission to intubation, discharge, or in-hospital death, up to 30 days.

• Accuracy Assessment of TRISS in Predicting Length of Hospitalization

  This outcome evaluates the ability of TRISS (range: 0-100% survival probability) to predict hospitalization duration. Patients with higher TRISS survival probabilities are expected to have shorter hospital stays, while those with lower probabilities are more likely to require prolonged hospitalization.

  From hospital admission to discharge, up to 30 days.

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

The study population will consist of trauma patients presenting to the Emergency Department of Al-Kadhmia Teaching Hospital during the study period. These patients represent a diverse demographic and clinical profile, encompassing individuals with varying injury mechanisms, severities, and outcomes. The study specifically targets patients for whom trauma scoring systems, including the Trauma and Injury Severity Score (TRISS), can be applied reliably. This includes both blunt and penetrating trauma cases.

You may qualify if:

• Trauma patients admitted to the emergency department of Al-Kadhimiya Teaching Hospital.
• Patients with adequate documentation of physiological and anatomical data are required for TRISS calculation.
• Trauma scoring (TRISS) completed within the first 6 hours of hospital arrival to ensure timely assessment.

You may not qualify if:

• Patients under 18 years, pregnant women, or those with conditions that alter standard trauma scoring or management.
• Non-trauma cases (e.g., medical emergencies, terminal illnesses) to ensure focus on trauma-specific outcomes.
• Patients with incomplete or missing data required for TRISS calculation.
• Patients declared dead on arrival or those not treated in the trauma and emergency department.
• Individuals refusing participation or withdrawing consent at any stage of the study.
• Patients transferred to or from another facility or enrolled in other studies that might affect scoring accuracy or outcomes.

Sponsors & Collaborators

• Al-Nahrain University: lead

Study Sites (1)

College of Medicine - Al-Nahrain University

Baghdad, 10001, Iraq

Location

Related Publications (18)

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Related Links

• Injuries and violence. 19 June 2024

MeSH Terms

Conditions

Multiple Trauma

Condition Hierarchy (Ancestors)

Wounds and Injuries

Study Officials

• Anees K Nile, Professor of general surgery

  College Of Medicine - Nahrain University

  STUDY DIRECTOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator

Study Record Dates

• First Submitted: November 23, 2024
• First Posted: December 2, 2024
• Study Start: November 15, 2024
• Primary Completion: July 1, 2025
• Study Completion: July 15, 2025
• Last Updated: March 6, 2026

Record last verified: 2026-03

Data Sharing

• IPD Sharing: Will not share

Locations

IR (1)