NCT06701513

Brief Summary

The purpose of this study is to assess the real-world effectiveness of deucravacitinib treatment in adults diagnosed with moderate-to-severe plaque psoriasis

Trial Health

80
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
350

participants targeted

Target at P75+ for all trials

Timeline
24mo left

Started Jan 2025

Typical duration for all trials

Geographic Reach
2 countries

48 active sites

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress40%
Jan 2025Apr 2028

First Submitted

Initial submission to the registry

November 20, 2024

Completed
2 days until next milestone

First Posted

Study publicly available on registry

November 22, 2024

Completed
2 months until next milestone

Study Start

First participant enrolled

January 29, 2025

Completed
3.3 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

April 30, 2028

Expected
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

April 30, 2028

Last Updated

May 18, 2026

Status Verified

May 1, 2026

Enrollment Period

3.3 years

First QC Date

November 20, 2024

Last Update Submit

May 15, 2026

Conditions

Keywords

Psoriasis

Outcome Measures

Primary Outcomes (3)

  • Physician's Global Assessment (PGA) 0/1 response

    Baseline and at months 4, 12, 18 (optional), and 24

  • Dermatology Life Quality Index (DLQI) 0/1 response

    Baseline and at months 4, 12, 18 (optional), and 24

  • Time from date of treatment initiation to date of discontinuation

    Up to 24 months

Secondary Outcomes (9)

  • Change in percentage involved Body Surface Area (BSA) from start of deucravacitinib treatment

    Baseline and at months 4, 12, 18 (optional), and 24

  • Change in patient reported symptom burden as assed by the 100-point Visual Analog Scale (VAS) - Itch

    Baseline and months 1, 4, 12, 18 (optional) and 24

  • Change in patient reported symptom burden as assed by the 100-point Visual Analog Scale (VAS) - Skin pain

    Baseline and months 1, 4, 12, 18 (optional) and 24

  • Change in patient reported symptom burden as assed by the 100-point Visual Analog Scale (VAS)] - Fatigue

    Baseline and months 1, 4, 12, 18 (optional) and 24

  • Physician's Global Assessment (PGA) score change from start of deucravacitinib treatment to follow-up

    Baseline and at months 4, 12, 18 (optional), and 24

  • +4 more secondary outcomes

Study Arms (1)

Participants that have initiated deucravacitinib treatment

Drug: Deucravacitinib

Interventions

As prescribed by treating clinician

Participants that have initiated deucravacitinib treatment

Eligibility Criteria

Age18 Years+
Sexall
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Adult patients who have been diagnosed with moderate-to-severe plaque psoriasis and who intend to start deucravacitinib treatment in France

You may qualify if:

  • ≥18 years of age
  • Physician-reported diagnosis of moderate to severe plaque psoriasis
  • Be newly initiating deucravacitinib
  • Do not object to participate

You may not qualify if:

  • Currently participating in or planning to participate in an interventional clinical trial
  • Previous treatment experience with deucravacitinib, including patients who received deucravacitinib as part of a blinded, randomized trial

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (48)

Chu Amiens Picardie - Site Sud

Amiens, 80054, France

RECRUITING

Cabinet Médical Elisabeth Lion

Angers, 49100, France

RECRUITING

Ch Victor Dupouy

Argenteuil, 95107, France

RECRUITING

Local Institution - 089

Argenteuil, 95107, France

COMPLETED

CH ARRAS

Arras, 62000, France

RECRUITING

Cabinet Dermatologie

Bordeaux, 33200, France

RECRUITING

Cabinet Dermatologie

Bordeaux, 33200, France

RECRUITING

Centre Hospitalier William Morey - Hématologie

Chalon-sur-Saône, 71100, France

RECRUITING

Local Institution - 053

Clermont-Ferrand, 63000, France

COMPLETED

CHU Dijon

Dijon, 21000, France

RECRUITING

Local Institution - 077

Dijon, 21000, France

NOT YET RECRUITING

CHU Grenoble Alps, Service de Dermatologie

La Tronche, 38700, France

RECRUITING

Local Institution - 014

Le Mans, 72037, France

NOT YET RECRUITING

CH Emile Roux

Le Puy-en-Velay, 43000, France

RECRUITING

Centre Hospitalier Lens

Lens, 62307, France

RECRUITING

Centre de santé Filieris

Marcq-en-Barœul, 59700, France

RECRUITING

Hopital Saint Eloi

Montpellier, 34295, France

RECRUITING

Tagast 41

Nice, 06000, France

RECRUITING

Ch Georges Renon

Niort, 79021, France

RECRUITING

Ch Georges Renon

Niort, 79021, France

RECRUITING

Hopital Caremeau

Nîmes, 30900, France

RECRUITING

Cabinet de dermatologie

Paris, 75012, France

RECRUITING

Local Institution - 086

Paris, 75012, France

COMPLETED

Hôpital Privé Francheville

Périgueux, 24000, France

RECRUITING

Centre Hospitalier de Roubaix

Roubaix, 59056, France

RECRUITING

Centre Hospitalier de Roubaix

Roubaix, 59056, France

RECRUITING

Local Institution - 031

Rouen, 76031, France

COMPLETED

Local Institution - 065

Saint-Germain-en-Laye, 78100, France

NOT YET RECRUITING

Hia Begin

Saint-Mandé, 94163, France

RECRUITING

Centre Dermatologique

Saint-Maur-des-Fossés, 94100, France

RECRUITING

Hia Sainte Anne

Toulon, 83800, France

RECRUITING

Hia Sainte Anne

Toulon, 83800, France

RECRUITING

Hopital Larrey

Toulouse, 31059, France

RECRUITING

Hopital Larrey

Toulouse, 31059, France

RECRUITING

Hopital Larrey

Toulouse, 31059, France

RECRUITING

Hopitaux de Brabois

Vandœuvre-lès-Nancy, 54511, France

RECRUITING

Hopitaux de Brabois

Vandœuvre-lès-Nancy, 54511, France

RECRUITING

Médipôle Hôpital Mutualiste

Villeurbanne, 69100, France

RECRUITING

Médipôle Hôpital Mutualiste

Villeurbanne, 69100, France

RECRUITING

Cabinet Medical

La Chaux-de-Fonds, 2300, Switzerland

RECRUITING

Cabinet Medical

La Chaux-de-Fonds, 2300, Switzerland

RECRUITING

Cabinet Medical

La Chaux-de-Fonds, 2300, Switzerland

RECRUITING

Cabinet Medical

La Chaux-de-Fonds, 2300, Switzerland

RECRUITING

Cabinet Medical

La Chaux-de-Fonds, 2300, Switzerland

RECRUITING

Cabinet Medical

La Chaux-de-Fonds, 2300, Switzerland

RECRUITING

Cabinet Medical

La Chaux-de-Fonds, 2300, Switzerland

RECRUITING

Local Institution - 056

La Chaux-de-Fonds, 2300, Switzerland

COMPLETED

Local Institution - 059

La Chaux-de-Fonds, 2300, Switzerland

COMPLETED

Related Links

MeSH Terms

Conditions

Psoriasis

Interventions

deucravacitinib

Condition Hierarchy (Ancestors)

Skin Diseases, PapulosquamousSkin DiseasesSkin and Connective Tissue Diseases

Study Officials

  • Bristol-Myers Squibb

    Bristol-Myers Squibb

    STUDY DIRECTOR

Central Study Contacts

BMS Clinical Trials Contact Center www.BMSClinicalTrials.com

CONTACT

First line of the email MUST contain NCT # and Site #.

CONTACT

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Target Duration
2 Years
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

November 20, 2024

First Posted

November 22, 2024

Study Start

January 29, 2025

Primary Completion (Estimated)

April 30, 2028

Study Completion (Estimated)

April 30, 2028

Last Updated

May 18, 2026

Record last verified: 2026-05

Data Sharing

IPD Sharing
Will not share

Locations