Study of the Incidence and Prognosis of Intrahospital Acute Kidney Injury
SIPARIO-1
1 other identifier
observational
43,000
1 country
1
Brief Summary
The goal of this observational study is to investigate the epidemiology of acute kidney injury in hospitalized patients. The main question it aims to answer is: how frequent is the development of acute kidney injury in patients who are hospitalized? Data from participants will be retrospectively collected from medical charts.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started Nov 2025
Typical duration for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
November 18, 2024
CompletedFirst Posted
Study publicly available on registry
November 20, 2024
CompletedStudy Start
First participant enrolled
November 25, 2025
CompletedPrimary Completion
Last participant's last visit for primary outcome
December 1, 2026
ExpectedStudy Completion
Last participant's last visit for all outcomes
December 1, 2027
March 27, 2026
March 1, 2026
1 year
November 18, 2024
March 25, 2026
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Incidence of intra-hospital Acute Kidney Injury
From 01/01/2019 to 12/31/2023
Secondary Outcomes (5)
Incidence of Acute Kidney Injury in different hospital wards
From 01/01/2019 to 12/31/2023
Association between Acute Kidney Injury development and major discharge diagnoses
From 01/01/2019 to 12/31/2023
Rate of re-hospitalisation in Acute Kidney Injury (AKI) and non-AKI patients
From 01/01/2019 to 12/31/2023
Intra-hospital mortality rate in patients who developed AKI compared to those who did not
From 01/01/2019 to 12/31/2023
Incidence of AKI associated with thrombotic microangiopathy
From 01/01/2019 to 12/31/2023
Study Arms (1)
Hospitalized Patients
All patients hospitalized from 01/01/2019 to 12/31/2023.
Eligibility Criteria
The study population consists of all patients admitted to the reference hospital during the indicated time frame; in particular, all patients for whom sufficient data are available to establish the presence or absence of a diagnosis of AKI will be considered.
You may qualify if:
- Patients hospitalised from 01/01/2019 to 31/12/2023
- Availability of a Hospital Discharge Form
- At least one serum creatinine (sCr) determination available
You may not qualify if:
- Day-hospital admission
- Discharge after an emergency room admission without hospital admission
- Stage IV and V CKD
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico
Milan, 20122, Italy
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- RETROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
November 18, 2024
First Posted
November 20, 2024
Study Start
November 25, 2025
Primary Completion (Estimated)
December 1, 2026
Study Completion (Estimated)
December 1, 2027
Last Updated
March 27, 2026
Record last verified: 2026-03