NCT06696859

Brief Summary

Antibiotics resistance has become a global health challenge especially in third world countries. The main causes of antibiotics resistance are the improper use or overuse of antibiotics, the lack of skilled public health workers and poor hygiene standards. Resistance to antibiotics reduces the effectiveness of these treatments and has a negative impact on hospital systems especially in intensive care settings. Medical intensive care unit (MICU) is commonly known as a "hotbed of infections" in high-risk healthcare environments ICU patients are especially prone to infections because of the various invasive procedures they undergo,including vascular access, mechanical ventilation, and intubation.

Trial Health

35
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
100

participants targeted

Target at P50-P75 for all trials

Timeline
Completed

Started Nov 2024

Shorter than P25 for all trials

Status
not yet recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

November 8, 2024

Completed
7 days until next milestone

Study Start

First participant enrolled

November 15, 2024

Completed
5 days until next milestone

First Posted

Study publicly available on registry

November 20, 2024

Completed
11 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

October 15, 2025

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

October 15, 2025

Completed
Last Updated

November 20, 2024

Status Verified

November 1, 2024

Enrollment Period

11 months

First QC Date

November 8, 2024

Last Update Submit

November 17, 2024

Conditions

Outcome Measures

Primary Outcomes (1)

  • Patterns of Antibiotics Resistance

    Number of resistance to antibiotics among ICU patients

    6months to 1 year

Interventions

Bacterial culture (sputum ,blood and pleural fluid) Antibiotics sensitivity tests

Eligibility Criteria

Sexall
Healthy VolunteersYes
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

All patients will be admitted at respiratory ICU with respiratory infection who have been treated with antibiotics and patients in whom adequate respiratory specimen

You may qualify if:

  • All patients will be admitted at respiratory ICU with respiratory infection who have been treated with antibiotics and patients in whom adequate respiratory specimen is obtained will be included in the study

You may not qualify if:

  • Patients who are HIV positive, who can't provide adequate respiratory specimen, patients who are not on antibiotics and patients who die within 48 hours after admission

Contact the study team to confirm eligibility.

Sponsors & Collaborators

MeSH Terms

Interventions

Anti-Bacterial Agents

Intervention Hierarchy (Ancestors)

Anti-Infective AgentsTherapeutic UsesPharmacologic ActionsChemical Actions and Uses

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
CROSS SECTIONAL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Resident at Chest Diseases Department

Study Record Dates

First Submitted

November 8, 2024

First Posted

November 20, 2024

Study Start

November 15, 2024

Primary Completion

October 15, 2025

Study Completion

October 15, 2025

Last Updated

November 20, 2024

Record last verified: 2024-11