Testing Carriage of Resistant Bacteria Using Swabs on Surfaces and Staff in a Complex Nursing Unit for Patients with Resistant Bacteria

NCT06696144 | Not Yet Recruiting

• 1 other identifier: SH-109-23
• Study Type: interventional
• Target: 20
• Locations: 0 countries
• Sites: N/A

Brief Summary

Impact of Care Team and Surfaces on the Spread of Resistant Bacteria in a Specialized Complex Nursing Unit for MDR Pathogen Carriers Background Multi-drug resistant (MDR) bacteria present a severe clinical and epidemiological challenge, typically managed through strict isolation and continuous monitoring. Transmission patterns among long-term care patients remain unclear. At "Shmuel Harofe" Geriatric Hospital, a dedicated MDR skilled care department was established to reduce infection risks in other hospital settings. It's uncertain if patients in this dedicated unit are more exposed to new bacterial colonizations. Contamination may stem from surfaces in rooms or shared spaces, or from the care team. Research Objectives

• Comparative analysis of bacterial carriage among staff in the MDR unit versus similar wards.
• Analysis of bacterial carriage frequency on surfaces in the MDR unit versus other wards using logistic regression models to assess the relationship between surface type and contamination levels. Ethics Informed consent will be obtained from staff for sample collection, with data anonymity preserved. Potential Contributions The study aims to clarify the roles of care staff and surfaces in transmitting resistant bacteria in dedicated units. Insights into transmission mechanisms may aid in developing improved protocols for patient and staff protection and provide recommendations for hygiene and control procedures in healthcare settings.

Conditions

Multi Drug Resistant Department; Multi Drug Resistant Bacteria

Keywords

MDR, VRE, CRE, older adults, long term care

Outcome Measures

Primary Outcomes (1)

• Number of positive swabs for CRE and VRE bacteria in care team members working in MDR units.

  Several swabs for VRE and CRE bacteria will be taken from personal items and skin from staff working in a MDR department to access if they serve as vectors for infection via skin carriage or personal items.

  3 month

Interventions

Skin swabs for multi drug resistant bacteria DIAGNOSTIC_TEST

Swabs from personal items or skin will be obtained from stuff and analyzed to detect CVE or VRE bacteria using Automated Susceptibility Testing

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

Sponsors & Collaborators

• Shmuel Harofeh Hospital, Geriatric Medical Center: lead

Central Study Contacts

Yochai Levy

CONTACT

972502991516; yochaylevi@mail.tau.ac.il

Nadya Kagansky

CONTACT

972506264678; batia_nadya.kagansky@moh.gov.il

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: SCREENING
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER GOV
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Hospital deputy director

Study Record Dates

• First Submitted: November 4, 2024
• First Posted: November 20, 2024
• Study Start: November 10, 2024
• Primary Completion: May 1, 2025
• Study Completion: July 1, 2025
• Last Updated: November 20, 2024

Record last verified: 2024-11

Data Sharing

• IPD Sharing: Will not share