Brief Summary

This study aimed to investigate whether concurrent tDCS over the PMC and PNS during action observation enhance observation-execution-related motor cortex excitability and improve motor performance, and to explore the underlying mechanism

Trial Health

On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment

128

participants targeted

Target at P50-P75 for not_applicable

Timeline

Completed

Started Oct 2017

Geographic Reach

1 country

1 active site

Status

completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

12 months study duration

Study Start

First participant enrolled

October 17, 2017

Completed

12 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

October 14, 2018

Completed

Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

October 14, 2018

Completed

6.1 years until next milestone

First Submitted

Initial submission to the registry

November 13, 2024

Completed

6 days until next milestone

First Posted

Study publicly available on registry

November 19, 2024

Completed

Last Updated

November 19, 2024

Status Verified

November 1, 2024

Enrollment Period

12 months

First QC Date

November 13, 2024

Last Update Submit

November 15, 2024

Conditions

Brain Stimulation Peripheral Nerve Stimulation Motor Observation Cortical Excitability

Outcome Measures

Primary Outcomes (4)

Motor-evoked potentials
Before interventions, and immediately after interventions
intracortical facilitation assessed by transcranial magnetic stimulation
Before interventions, and immediately after interventions
short-interval intracortical inhibition assessed by transcranial magnetic stimulation
Before interventions, and immediately after interventions
Reaction times of action execution blocks
immediately after interventions

Study Arms (5)

tDCS + PNS with action observation

EXPERIMENTAL

Device: tDCS + PNS without action observation

sham tDCS + sham PNS with action observation

EXPERIMENTAL

Device: sham tDCS + sham PNS with action observation

tDCS + PNS without action observation

EXPERIMENTAL

Device: sham tDCS + PNS with action observation

sham tDCS + PNS with action observation

ACTIVE COMPARATOR

Device: tDCS + PNS with action observation

tDCS + sham PNS with action observation

ACTIVE COMPARATOR

Device: tDCS + sham PNS with action observation